New steroids and sesquiterpene from Turraea pubescens
Yuan, Chun-Mao1,2; Tang, Gui-Hua2; Wang, Xiao-Ying2; Zhang, Yu2; Cao, Ming-Ming2; Li, Xiao-Hui2; Li, Yan2; Li, Shun-Lin2; Di, Ying-Tong2; He, Hong-Ping2; Hao, Xiao-Jiang2; Hua, Hui-Ming1
Corresponding AuthorHe,HP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.,hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn ; huimhua@163.com
2013-10-01
Source PublicationFITOTERAPIA
ISSN0367-326X
Volume90Pages:119-125
AbstractFour new compounds, including three new steroids (1-3) and one new sesquiterpene (6), and two new natural products (4-5), as well as three known steroids (7-9) were isolated from the twigs of Turraea pubescens. Compounds 3-5 are C-22 steroids isolated from the Meliaceae family for the first time. Their structures were elucidated by extensive NMR and MS analyses. Compound 1 exhibited inhibitory activity against lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells with an IC50 value of 11.5 mu M. (C) 2013 Elsevier B.V. All rights reserved.
KeywordTurraea Pubescens Meliaceae Steroids Sesquiterpene Anti-inflammatory
Subject AreaPharmacology & Pharmacy
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000326427600016
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/17416
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
Recommended Citation
GB/T 7714
Yuan, Chun-Mao,Tang, Gui-Hua,Wang, Xiao-Ying,et al. New steroids and sesquiterpene from Turraea pubescens[J]. FITOTERAPIA,2013,90:119-125.
APA Yuan, Chun-Mao.,Tang, Gui-Hua.,Wang, Xiao-Ying.,Zhang, Yu.,Cao, Ming-Ming.,...&Hua, Hui-Ming.(2013).New steroids and sesquiterpene from Turraea pubescens.FITOTERAPIA,90,119-125.
MLA Yuan, Chun-Mao,et al."New steroids and sesquiterpene from Turraea pubescens".FITOTERAPIA 90(2013):119-125.
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