Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia
Huang, Sheng-Zhuo1,4; Zhang, Xuan3; Ma, Qing-Yun1,4; Zheng, Yong-Tang3; Xu, Feng-Qing2; Peng, Hua2; Dai, Hao-Fu1,4; Zhou, Jun2; Zhao, You-Xing1,4
2013-12-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号91页码:224-230
摘要Five new diterpenoids named excocarinols A-E (1-5) including three pimaranes, one cleistanthane, and one nor-beyerane, together with nine known compounds, were isolated from the EtOAc extract of the Chinese ethnodrug Gua-jing-ban (Excoecaria acerifolia Didr.). Their structures were elucidated by the analysis of spectroscopic data including 1D, 2D NMR and HR-MS. The anti-HIV-1 bioassay on the diterpenoids showed that excocarinol A (1) exhibited moderate anti-HIV-1 activity with EC50 5.58 mu M and SI (Selection Index) over 112.71. Crown Copyright (C) 2013 Published by Elsevier B.V. All rights reserved.
关键词Excoecaria Acerifolia Euphorbiaceae Anti-hiv Diterpenoid Triterpenoid
资助信息Special Fund for Agro-scientific Research in the Public Interest [201303117];National Support Science and Technology Subject [2013BAI11B04];Fundamental Scientific Research Funds for CATAS [1630052013001, ITBB110301]
学科领域Pharmacology & Pharmacy
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000327574300033
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/17402
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
3.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech Chinese Acad, Kunming Inst Zool, Kunming 650223, Peoples R China
4.Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Haikou 571101, Peoples R China
推荐引用方式
GB/T 7714
Huang, Sheng-Zhuo,Zhang, Xuan,Ma, Qing-Yun,et al. Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia[J]. FITOTERAPIA,2013,91:224-230.
APA Huang, Sheng-Zhuo.,Zhang, Xuan.,Ma, Qing-Yun.,Zheng, Yong-Tang.,Xu, Feng-Qing.,...&Zhao, You-Xing.(2013).Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia.FITOTERAPIA,91,224-230.
MLA Huang, Sheng-Zhuo,et al."Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia".FITOTERAPIA 91(2013):224-230.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
1-s2.0-S0367326X1300(583KB) 开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Huang, Sheng-Zhuo]的文章
[Zhang, Xuan]的文章
[Ma, Qing-Yun]的文章
百度学术
百度学术中相似的文章
[Huang, Sheng-Zhuo]的文章
[Zhang, Xuan]的文章
[Ma, Qing-Yun]的文章
必应学术
必应学术中相似的文章
[Huang, Sheng-Zhuo]的文章
[Zhang, Xuan]的文章
[Ma, Qing-Yun]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。