Nortriterpenoids from Schisandra wilsoniana
Yang, Guang-Yu1,2; Xiao, Wei-Lie1; Chang, Ying3; Wang, Rui-Rui4,5; Pu, Jian-Xin1; Gao, Xue-Mei1,2; Lei, Chun1; Lu, Yang3; Zheng, Yong-Tang4,5; Sun, Han-Dong1
AbstractThree new highly oxygenated nortriterpenoids, wilsonianadilactones A-C (1-3), together with twelve known ones, i.e., 4-15, were isolated from the leaves and stems of Schisandra wilsoniana. Their structures were established by means of extensive analysis of spectroscopic data, and compound I was further confirmed by X-ray crystallographic diffraction. Compounds 1-3 showed weak anti-HIV-1 activity with EC(50) values of 23.5, 55.5, and 66.4 mu g/ml, respectively.
KeywordAnti-hiv Activity Highly Oxygenated Nortriterpenoids Unique Skeleton Lancifolia Chinensis Micrantha
Subject AreaChemistry ; Multidisciplinary
Indexed BySCI ; IC
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000261050300007
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Cited Times:20[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
4.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China
5.Chinese Acad Sci, Kunming Inst Zool, Lab Mol Immunopharmacol, Kunming 650223, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Yang, Guang-Yu,Xiao, Wei-Lie,Chang, Ying,et al. Nortriterpenoids from Schisandra wilsoniana[J]. HELVETICA CHIMICA ACTA,2008,91(10):1871-1878.
APA Yang, Guang-Yu.,Xiao, Wei-Lie.,Chang, Ying.,Wang, Rui-Rui.,Pu, Jian-Xin.,...&Sun, Han-Dong.(2008).Nortriterpenoids from Schisandra wilsoniana.HELVETICA CHIMICA ACTA,91(10),1871-1878.
MLA Yang, Guang-Yu,et al."Nortriterpenoids from Schisandra wilsoniana".HELVETICA CHIMICA ACTA 91.10(2008):1871-1878.
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