Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens
Yuan, Chun-Mao1,2; Tang, Gui-Hua1; Zhang, Yu1; Wang, Xiao-Ying1; Cao, Ming-Ming1; Guo, Feng1; Li, Yan1; Di, Ying-Tong1; Li, Shun-Lin1; Hua, Hui-Ming2; He, Hong-Ping1; Hao, Xiao-Jiang1
Corresponding AuthorHua, HM (reprint author), Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China. ; huimhua@163.com ; hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
2013-06-01
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume76Issue:6Pages:1166-1174
AbstractEleven new limonoids, turrapubins A-K (1-11), and three new triterpenoids (12-14), along with 14 known compounds, were isolated from the twigs of Turraea pubescens. The structures of 1-14 were elucidated on the basis of NMR and MS analysis. Compounds 12, 16, 18, and 19 exhibited inhibitory activities against lipopolysaccharide-induced nitric oxide production in RAW264.7 cells. In addition, compounds 2, 11, 18, and 26 exhibited inhibitory activities against brine shrimp larvae (Artemia salina) at 100 ppm with the corrected mortality ranging from 81.7% to 100%.
KeywordTirucallane Triterpenoids Cipadessa-baccifera Khaya-senegalensis Azadirachta-indica Brucea-javanica Melia-toosendan A-j Floribunda Terpenoids Alkaloids
Subject AreaPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np400276q
Indexed BySCI ; IC
Language英语
WOS IDWOS:000321320600024
Citation statistics
Cited Times:15[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/16775
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China
Recommended Citation
GB/T 7714
Yuan, Chun-Mao,Tang, Gui-Hua,Zhang, Yu,et al. Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(6):1166-1174.
APA Yuan, Chun-Mao.,Tang, Gui-Hua.,Zhang, Yu.,Wang, Xiao-Ying.,Cao, Ming-Ming.,...&Hao, Xiao-Jiang.(2013).Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens.JOURNAL OF NATURAL PRODUCTS,76(6),1166-1174.
MLA Yuan, Chun-Mao,et al."Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens".JOURNAL OF NATURAL PRODUCTS 76.6(2013):1166-1174.
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