Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens
Yuan, Chun-Mao1,2; Tang, Gui-Hua1; Zhang, Yu1; Wang, Xiao-Ying1; Cao, Ming-Ming1; Guo, Feng1; Li, Yan1; Di, Ying-Tong1; Li, Shun-Lin1; Hua, Hui-Ming2; He, Hong-Ping1; Hao, Xiao-Jiang1
2013-06-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号76期号:6页码:1166-1174
摘要Eleven new limonoids, turrapubins A-K (1-11), and three new triterpenoids (12-14), along with 14 known compounds, were isolated from the twigs of Turraea pubescens. The structures of 1-14 were elucidated on the basis of NMR and MS analysis. Compounds 12, 16, 18, and 19 exhibited inhibitory activities against lipopolysaccharide-induced nitric oxide production in RAW264.7 cells. In addition, compounds 2, 11, 18, and 26 exhibited inhibitory activities against brine shrimp larvae (Artemia salina) at 100 ppm with the corrected mortality ranging from 81.7% to 100%.
关键词Tirucallane Triterpenoids Cipadessa-baccifera Khaya-senegalensis Azadirachta-indica Brucea-javanica Melia-toosendan A-j Floribunda Terpenoids Alkaloids
资助信息National Natural Science Foundation of China [30830114]; Ministry of Science and Technology [2009CB522300, 2009CB940900]; Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047]
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16775
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China
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Yuan, Chun-Mao,Tang, Gui-Hua,Zhang, Yu,et al. Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(6):1166-1174.
APA Yuan, Chun-Mao.,Tang, Gui-Hua.,Zhang, Yu.,Wang, Xiao-Ying.,Cao, Ming-Ming.,...&Hao, Xiao-Jiang.(2013).Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens.JOURNAL OF NATURAL PRODUCTS,76(6),1166-1174.
MLA Yuan, Chun-Mao,et al."Bioactive Limonoid and Triterpenoid Constituents of Turraea pubescens".JOURNAL OF NATURAL PRODUCTS 76.6(2013):1166-1174.
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