Diterpenoids from the Twigs and Leaves of Fokienia hodginsii
Wu, Xing-De1; He, Juan1; Li, Xing-Yao1; Dong, Liao-Bin1; Gong, Xun1; Song, Liu-Dong2,3; Li, Yan1; Peng, Li-Yan1; Zhao, Qin-Shi1
2013-06-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号76期号:6页码:1032-1038
摘要Five new isopimarane diterpenoids, fokihodgins A-E (1-5), four new labdane diterpenoids, fokihodgins F-I (6-9), and one new icetexane diterpenoid, fokihodgin J (10), as well as 18 known diterpenoids were isolated from Fokienia hodginsii. The structures of the new compounds were determined on the basis of their spectroscopic analysis, and the absolute configurations of 1 and 6 were established by X-ray crystallographic analysis. Compound 9 showed moderate cytotoxicity against HL-60 and SMMC-7721 cell lines, with IC50 values of 9.10 and 7.50 mu M, respctively.
关键词Antibacterial Activity Cupressaceae Derivatives Terpenes Abietane Labdanes Lignans Growth Cones Bark
资助信息National Basic Research Program of China (973 Program) [2011CB915503, 2009CB522303]; National Natural Science Foundation of China [U0932602, 90813004]
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16771
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Peoples R China
2.Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Peoples R China
3.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Peoples R China
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Wu, Xing-De,He, Juan,Li, Xing-Yao,et al. Diterpenoids from the Twigs and Leaves of Fokienia hodginsii[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(6):1032-1038.
APA Wu, Xing-De.,He, Juan.,Li, Xing-Yao.,Dong, Liao-Bin.,Gong, Xun.,...&Zhao, Qin-Shi.(2013).Diterpenoids from the Twigs and Leaves of Fokienia hodginsii.JOURNAL OF NATURAL PRODUCTS,76(6),1032-1038.
MLA Wu, Xing-De,et al."Diterpenoids from the Twigs and Leaves of Fokienia hodginsii".JOURNAL OF NATURAL PRODUCTS 76.6(2013):1032-1038.
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