| Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity | |
Li, Shi-Fei1,2; Zhang, Yu1 ; Huang, Ning2,3; Zheng, Yong-Tang3; Di, Ying-Tong1; Li, Shun-Lin1; Cheng, Yuan-Yuan1,2; He, Hong-Ping1; Hao, Xiao-Jiang1
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| Corresponding Author | He, HP (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China. ; hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
| 2013-09-01 | |
| Source Publication | PHYTOCHEMISTRY
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| ISSN | 0031-9422 |
| Volume | 93Pages:216-221 |
| Abstract | Thirteen highly oxygenated daphnane diterpenoids, including six known compounds, were isolated from the stems of Trigonostemon lii. The structures were elucidated by extensive spectroscopic analyses including 2D NMR spectroscopy (HSQC, H-1-H-1 COSY, HMBC, and ROESY) and mass spectrometry. The absolute stereochemistries of compounds were established on the basis of CD spectra. Four of the compounds showed modest anti-HIV-1 activity (EC50 = 2.04, 9.17, 11.42, and 9.05 mu g/ml, TI = 26.49, >21.81, 9.32, and 9.56, respectively) in vitro. (C) 2013 Elsevier Ltd. All rights reserved. |
| Keyword | Trigonostemon Lii Euphorbiaceae Daphnane Diterpenoids Trigolins A-g Anti-hiv-1 Activity |
| Subject Area | Biochemistry & Molecular Biology ; Plant Sciences |
| DOI | 10.1016/j.phytochem.2013.03.003 |
| Indexed By | SCI ; IC |
| Language | 英语 |
| WOS ID | WOS:000323630000025 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/16685 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Chinese Acad Sci & Yunnan Prov, Kunming 650223, Yunnan, Peoples R China |
| Recommended Citation GB/T 7714 | Li, Shi-Fei,Zhang, Yu,Huang, Ning,et al. Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity[J]. PHYTOCHEMISTRY,2013,93:216-221. |
| APA | Li, Shi-Fei.,Zhang, Yu.,Huang, Ning.,Zheng, Yong-Tang.,Di, Ying-Tong.,...&Hao, Xiao-Jiang.(2013).Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity.PHYTOCHEMISTRY,93,216-221. |
| MLA | Li, Shi-Fei,et al."Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity".PHYTOCHEMISTRY 93(2013):216-221. |
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