Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity

doi:10.1016/j.phytochem.2013.03.003

	Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity
	Li, Shi-Fei 1,2; Zhang, Yu1 ; Huang, Ning 2,3; Zheng, Yong-Tang 3; Di, Ying-Tong1 ; Li, Shun-Lin 1; Cheng, Yuan-Yuan 1,2; He, Hong-Ping 1; Hao, Xiao-Jiang1
通讯作者	He, HP (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China. ; hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
	2013-09-01
发表期刊	PHYTOCHEMISTRY
ISSN	0031-9422
卷号	93 页码:216-221
摘要	Thirteen highly oxygenated daphnane diterpenoids, including six known compounds, were isolated from the stems of Trigonostemon lii. The structures were elucidated by extensive spectroscopic analyses including 2D NMR spectroscopy (HSQC, H-1-H-1 COSY, HMBC, and ROESY) and mass spectrometry. The absolute stereochemistries of compounds were established on the basis of CD spectra. Four of the compounds showed modest anti-HIV-1 activity (EC50 = 2.04, 9.17, 11.42, and 9.05 mu g/ml, TI = 26.49, >21.81, 9.32, and 9.56, respectively) in vitro. (C) 2013 Elsevier Ltd. All rights reserved.
关键词	Trigonostemon Lii Euphorbiaceae Daphnane Diterpenoids Trigolins A-g Anti-hiv-1 Activity
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
DOI	10.1016/j.phytochem.2013.03.003
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000323630000025
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/16685
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Chinese Acad Sci & Yunnan Prov, Kunming 650223, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Li, Shi-Fei,Zhang, Yu,Huang, Ning,et al. Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity[J]. PHYTOCHEMISTRY,2013,93:216-221.
APA	Li, Shi-Fei.,Zhang, Yu.,Huang, Ning.,Zheng, Yong-Tang.,Di, Ying-Tong.,...&Hao, Xiao-Jiang.(2013).Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity.PHYTOCHEMISTRY,93,216-221.
MLA	Li, Shi-Fei,et al."Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity".PHYTOCHEMISTRY 93(2013):216-221.

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