| Acortatarin A inhibits high glucose-induced extracellular matrix production in mesangial cells | |
| Zhao Zhi-fang1; Zhou Li-li1; Chen Xia1; Cheng Yong-xian2; Hou Fan-fan1; Nie Jing1 | |
| 通讯作者 | Nie, J (reprint author), Nanfang Hosp, Div Nephrol, Guangzhou 510515, Guangdong, Peoples R China. ; jingnie2006@163.com |
| 2013-04-05 | |
| 发表期刊 | CHINESE MEDICAL JOURNAL
 |
| ISSN | 0366-6999 |
| 卷号 | 126期号:7页码:1230-1235 |
| 摘要 | Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Various treatment regimens and combinations of therapies provide only partial renoprotection. Therefore new approaches are needed to retard the progression of DN. The aim of the present study was to evaluate the role of a novel spiroalkaloid from Acorus tatarinowii named acortatarin A (AcorA) in inhibiting high glucose-induced extracellular matrix accumulation in mesangial cells (MCs). |
| 关键词 | Acortatarin a High Glucose Mesangial Cells Extracellular Matrix |
| 学科领域 | Medicine, General & Internal |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000319783800006 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/16579 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Southern Med Univ, Res Inst Nephrol Guangdong Prov, Key Lab Organ Failure Res, Div Nephrol,Nanfang Hosp,Minist Educ, Guangzhou 510515, Guangdong, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao Zhi-fang,Zhou Li-li,Chen Xia,et al. Acortatarin A inhibits high glucose-induced extracellular matrix production in mesangial cells[J]. CHINESE MEDICAL JOURNAL,2013,126(7):1230-1235. |
| APA | Zhao Zhi-fang,Zhou Li-li,Chen Xia,Cheng Yong-xian,Hou Fan-fan,&Nie Jing.(2013).Acortatarin A inhibits high glucose-induced extracellular matrix production in mesangial cells.CHINESE MEDICAL JOURNAL,126(7),1230-1235. |
| MLA | Zhao Zhi-fang,et al."Acortatarin A inhibits high glucose-induced extracellular matrix production in mesangial cells".CHINESE MEDICAL JOURNAL 126.7(2013):1230-1235. |
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