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题名: Acortatarin A inhibits high glucose-induced extracellular matrix production in mesangial cells
作者: Zhao Zhi-fang1; Zhou Li-li1; Chen Xia1; null(程永现)2; Hou Fan-fan1; Nie Jing1
刊名: CHINESE MEDICAL JOURNAL
关键词: acortatarin A ; high glucose ; mesangial cells ; extracellular matrix
英文摘要: Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Various treatment regimens and combinations of therapies provide only partial renoprotection. Therefore new approaches are needed to retard the progression of DN. The aim of the present study was to evaluate the role of a novel spiroalkaloid from Acorus tatarinowii named acortatarin A (AcorA) in inhibiting high glucose-induced extracellular matrix accumulation in mesangial cells (MCs).
出版日期: 2013-04-05
卷号: 126, 期号:7, 页码:1230-1235
语种: 英语
ISSN号: 0366-6999
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/16579
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Southern Med Univ, Res Inst Nephrol Guangdong Prov, Key Lab Organ Failure Res, Div Nephrol,Nanfang Hosp,Minist Educ, Guangzhou 510515, Guangdong, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China

Recommended Citation:
Zhao Zhi-fang; Zhou Li-li; Chen Xia; Cheng Yong-xian; Hou Fan-fan; Nie Jing.Acortatarin A inhibits high glucose-induced extracellular matrix production in mesangial cells,CHINESE MEDICAL JOURNAL,2013,126(7):1230-1235
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