Bioactive Abietane and ent-Kaurane Diterpenoids from Isodon tenuifolius
Yang, Jian-Hong1,2; Du, Xue1; He, Fei1; Zhang, Hai-Bo1; Li, Xiao-Nian1; Su, Jia1; Li, Yan1; Pu, Jian-Xin1; Sun, Han-Dong1
2013-02-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号76期号:2页码:256-264
摘要Three new abietane diterpenoids, isoabietenins A-C (1-3), and 13 new ent-kauranoids, tenuifolins A-M (4-16), along with four known compounds (17-20), were isolated from the aerial parts of Isodon tenuifolius. The structures of the new metabolites were established on the basis of detailed spectroscopic analysis. The absolute configurations of 1, 15, and 16 were confirmed by single-crystal X-ray diffraction. Selected compounds were evaluated for their cytotoxicity against a small panel of human tumor cell lines, and some compounds showed inhibitory effects. Furthermore, several isolates exhibited inhibitory activity against nitric oxide production in LPS-activated RAW264.7 macrophages.
关键词Adenantha
资助信息NSFC-Joint Foundation of Yunnan Province [U0832602]; National Natural Science Foundation of China [81172939]; Major State Basic Research Development Program of China [2009CB522300]; Reservation-Talent Project of Yunnan Province [2011CI043]; Major Direction Projection Foundation of CAS Intellectual Innovation Project [KSCX2-EW-J-24]
学科领域Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000315431800018
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16543
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Yang, Jian-Hong,Du, Xue,He, Fei,et al. Bioactive Abietane and ent-Kaurane Diterpenoids from Isodon tenuifolius[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(2):256-264.
APA Yang, Jian-Hong.,Du, Xue.,He, Fei.,Zhang, Hai-Bo.,Li, Xiao-Nian.,...&Sun, Han-Dong.(2013).Bioactive Abietane and ent-Kaurane Diterpenoids from Isodon tenuifolius.JOURNAL OF NATURAL PRODUCTS,76(2),256-264.
MLA Yang, Jian-Hong,et al."Bioactive Abietane and ent-Kaurane Diterpenoids from Isodon tenuifolius".JOURNAL OF NATURAL PRODUCTS 76.2(2013):256-264.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2013072430.pdf(863KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Yang, Jian-Hong]的文章
[Du, Xue]的文章
[He, Fei]的文章
百度学术
百度学术中相似的文章
[Yang, Jian-Hong]的文章
[Du, Xue]的文章
[He, Fei]的文章
必应学术
必应学术中相似的文章
[Yang, Jian-Hong]的文章
[Du, Xue]的文章
[He, Fei]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。