| Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia | |
Wang, Xiao-Ying1,2; Tang, Gui-Hua2 ; Yuan, Chun-Mao2; Zhang, Yu2; Zou, Tao1; Yu, Chun1; Zhao, Qing1; Hao, Xiao-Jiang; He, Hong-Ping1,2
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| 通讯作者 | Zhao, Q (reprint author), Yunnan Univ TCM, Fac Pharm, Kunming 650500, Yunnan, Peoples R China. ; tempzhao@126.com ; haoxj@mail.kib.ac.cn ; hehongping@mail.kib.ac.cn |
| 2013-03-01 | |
| 发表期刊 | FITOTERAPIA
 |
| ISSN | 0367-326X |
| 卷号 | 85页码:64-68 |
| 摘要 | Three new cycloartane triterpenoids, aphagrandinoids A-C (1-3), and a new natural product, aphagrandinoid D (4), together with a known compound, were isolated from the leaves and twigs of Aphanamixis grandifolia. Their structures were elucidated by extensive NMR and MS techniques. Aphagrandinoid A (1), a 29-nor-cycloart triterpenoid, features with a sprio ring system at the side chain, while aphagrandinoid C (3) is a pentnortriterpenoid. Antibacterial activities of these five compounds were also evaluated. Compounds 1 and 5 showed weak antibacterial activities (MIC values: 1.57-3.13 mu g/mL) against Staphylococcus aureus, MRSA 92(#), and MRSA 98(#). (C) 2013 Elsevier B.V. All rights reserved. |
| 关键词 | Aphanamixis Grandifolia Meliaceae Cycloartane Triterpenoids Antibacterial Activities |
| 学科领域 | Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000317172000010 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/16453 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Yunnan Univ TCM, Fac Pharm, Kunming 650500, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xiao-Ying,Tang, Gui-Hua,Yuan, Chun-Mao,et al. Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia[J]. FITOTERAPIA,2013,85:64-68. |
| APA | Wang, Xiao-Ying.,Tang, Gui-Hua.,Yuan, Chun-Mao.,Zhang, Yu.,Zou, Tao.,...&He, Hong-Ping.(2013).Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia.FITOTERAPIA,85,64-68. |
| MLA | Wang, Xiao-Ying,et al."Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia".FITOTERAPIA 85(2013):64-68. |
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