Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia
Wang, Xiao-Ying1,2; Tang, Gui-Hua2; Yuan, Chun-Mao2; Zhang, Yu2; Zou, Tao1; Yu, Chun1; Zhao, Qing1; Hao, Xiao-Jiang; He, Hong-Ping1,2
Corresponding AuthorZhao, Q (reprint author), Yunnan Univ TCM, Fac Pharm, Kunming 650500, Yunnan, Peoples R China. ; tempzhao@126.com ; haoxj@mail.kib.ac.cn ; hehongping@mail.kib.ac.cn
2013-03-01
Source PublicationFITOTERAPIA
ISSN0367-326X
Volume85Pages:64-68
AbstractThree new cycloartane triterpenoids, aphagrandinoids A-C (1-3), and a new natural product, aphagrandinoid D (4), together with a known compound, were isolated from the leaves and twigs of Aphanamixis grandifolia. Their structures were elucidated by extensive NMR and MS techniques. Aphagrandinoid A (1), a 29-nor-cycloart triterpenoid, features with a sprio ring system at the side chain, while aphagrandinoid C (3) is a pentnortriterpenoid. Antibacterial activities of these five compounds were also evaluated. Compounds 1 and 5 showed weak antibacterial activities (MIC values: 1.57-3.13 mu g/mL) against Staphylococcus aureus, MRSA 92(#), and MRSA 98(#). (C) 2013 Elsevier B.V. All rights reserved.
KeywordAphanamixis Grandifolia Meliaceae Cycloartane Triterpenoids Antibacterial Activities
Subject AreaPharmacology & Pharmacy
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000317172000010
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/16453
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Yunnan Univ TCM, Fac Pharm, Kunming 650500, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Wang, Xiao-Ying,Tang, Gui-Hua,Yuan, Chun-Mao,et al. Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia[J]. FITOTERAPIA,2013,85:64-68.
APA Wang, Xiao-Ying.,Tang, Gui-Hua.,Yuan, Chun-Mao.,Zhang, Yu.,Zou, Tao.,...&He, Hong-Ping.(2013).Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia.FITOTERAPIA,85,64-68.
MLA Wang, Xiao-Ying,et al."Aphagrandinoids A-D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia".FITOTERAPIA 85(2013):64-68.
Files in This Item: Download All
File Name/Size DocType Version Access License
Wang-2013-Aphagrandi(644KB) 开放获取--View Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, Xiao-Ying]'s Articles
[Tang, Gui-Hua]'s Articles
[Yuan, Chun-Mao]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, Xiao-Ying]'s Articles
[Tang, Gui-Hua]'s Articles
[Yuan, Chun-Mao]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, Xiao-Ying]'s Articles
[Tang, Gui-Hua]'s Articles
[Yuan, Chun-Mao]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Wang-2013-Aphagrandinoids A-D.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.