Dendrowardols A and B, two new sesquiterpenoids from Dendrobium wardianum Warner
Fan, Wei-Wei1,2; Xu, Feng-Qing1,2; Dong, Fa-Wu1,2; Li, Xiao-Nian1; Wei, Xiao-Yong3; Zhou, Jun1; Hu, Jiang-Miao1
2013-04-10
发表期刊TETRAHEDRON LETTERS
ISSN0040-4039
卷号54期号:15页码:1928-1930
摘要Two structurally unique sesquiterpenoids, dendrowardols A (1) and B (2), both possessing an unprecedented 5/7/4 tricyclic ring system, together with a known biogenetically related sesquiterpenoid, 10 beta,12,14-trihydroxy alloaromadendrane (3), were isolated from the stems of Dendrobium wardianum Warner. The structures of 1 and 2 were established on the basis of spectroscopic data. The absolute configuration of 1 and the relative configuration of 2 were determined by single-crystal X-ray diffraction crystallography. The hypothetical biosynthetic pathways of 1 and 2 were postulated. The effect on the proliferation of human lens epithelial cells (HLECs) induced by D-galactose of compound 2 was evaluated by an MTT assay. Crown Copyright (c) 2013 Published by Elsevier Ltd. All rights reserved.
关键词Dendrobium Wardianum Warner Sesquiterpenoids Biosynthetic Pathways
资助信息National Natural and Science Foundations of China [30800090]; 'Xi-Bu-Zhi-Guang' project from Chinese Academy of Sciences [2009312D11017]; Fund of State Key Laboratory of Phytochemistry and Plant Resource in West China [P2010-ZZ012]
收录类别SCI ; IC
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/16427
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Guangzhou Univ Chinese Med, Guangzhou 510006, Guangdong, Peoples R China
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Fan, Wei-Wei,Xu, Feng-Qing,Dong, Fa-Wu,et al. Dendrowardols A and B, two new sesquiterpenoids from Dendrobium wardianum Warner[J]. TETRAHEDRON LETTERS,2013,54(15):1928-1930.
APA Fan, Wei-Wei.,Xu, Feng-Qing.,Dong, Fa-Wu.,Li, Xiao-Nian.,Wei, Xiao-Yong.,...&Hu, Jiang-Miao.(2013).Dendrowardols A and B, two new sesquiterpenoids from Dendrobium wardianum Warner.TETRAHEDRON LETTERS,54(15),1928-1930.
MLA Fan, Wei-Wei,et al."Dendrowardols A and B, two new sesquiterpenoids from Dendrobium wardianum Warner".TETRAHEDRON LETTERS 54.15(2013):1928-1930.
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