Alkaloids from Melodinus yunnanensis

doi:10.1016/j.phytochem.2012.06.013

	Alkaloids from Melodinus yunnanensis
	Cai, Xiang-Hai; Li, Yan; Liu, Ya-Ping; Li, Xiao-Ning; Bao, Mei-Fen; Luo, Xiao-Dong
通讯作者	Cai, XH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China.,xhcai@mail.kib.ac.cn ; xdluo@mail.kib.ac.cn
	2012-11-01
发表期刊	PHYTOCHEMISTRY
ISSN	0031-9422
卷号	83 页码:116-124
摘要	Ten monoterpenoid indole alkaloids, namely meloyine, 19S-methoxytubotaiwine N-4-oxide, 16,19-epoxy-Delta(14)-vincanol, 14 beta-hydroxymeloyunine, meloyunine, Delta(14)-vincamenine N-4-oxide, 16 beta,21 beta-epoxy-vincadine, 14 beta,15 beta-20S-quebrachamine, 3-oxo-voaphylline, 2 alpha,7 alpha-dihydroxy-dihydrovoaphylline, and 32 known alkaloids were isolated from leaves and twigs of Melodious yunnanensis. Their structures were elucidated based on 1- and 2-D NMR, FTIR, UV, and MS spectroscopic data. Meloyine I showed weak cytotoxic activity against four human cancer cell lines: MCF-7 breast cancer, SMMC-7721 hepatocellular carcinoma, HL-60 myeloid leukemia, and A-549 lung cancer. (C) 2012 Elsevier Ltd. All rights reserved.
关键词	Melodinus Yunnanensis Apocynaceae Monoterpenoid Indole Alkaloid Structure Elucidation Cytotoxicity
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
DOI	10.1016/j.phytochem.2012.06.013
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000310421100014
引用统计	被引频次：45[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/15934
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Cai, Xiang-Hai,Li, Yan,Liu, Ya-Ping,et al. Alkaloids from Melodinus yunnanensis[J]. PHYTOCHEMISTRY,2012,83:116-124.
APA	Cai, Xiang-Hai,Li, Yan,Liu, Ya-Ping,Li, Xiao-Ning,Bao, Mei-Fen,&Luo, Xiao-Dong.(2012).Alkaloids from Melodinus yunnanensis.PHYTOCHEMISTRY,83,116-124.
MLA	Cai, Xiang-Hai,et al."Alkaloids from Melodinus yunnanensis".PHYTOCHEMISTRY 83(2012):116-124.

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