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题名: Alkaloids from Melodinus yunnanensis
作者: null(蔡祥海)1; null(李艳)1; Liu, Ya-Ping1; Li, Xiao-Ning1; Bao, Mei-Fen1; null(罗晓东)1
刊名: PHYTOCHEMISTRY
关键词: Melodinus yunnanensis ; Apocynaceae ; Monoterpenoid indole alkaloid ; Structure elucidation ; Cytotoxicity
英文摘要: Ten monoterpenoid indole alkaloids, namely meloyine, 19S-methoxytubotaiwine N-4-oxide, 16,19-epoxy-Delta(14)-vincanol, 14 beta-hydroxymeloyunine, meloyunine, Delta(14)-vincamenine N-4-oxide, 16 beta,21 beta-epoxy-vincadine, 14 beta,15 beta-20S-quebrachamine, 3-oxo-voaphylline, 2 alpha,7 alpha-dihydroxy-dihydrovoaphylline, and 32 known alkaloids were isolated from leaves and twigs of Melodious yunnanensis. Their structures were elucidated based on 1- and 2-D NMR, FTIR, UV, and MS spectroscopic data. Meloyine I showed weak cytotoxic activity against four human cancer cell lines: MCF-7 breast cancer, SMMC-7721 hepatocellular carcinoma, HL-60 myeloid leukemia, and A-549 lung cancer. (C) 2012 Elsevier Ltd. All rights reserved.
出版日期: 2012-11-01
卷号: 83, 页码:116-124
DOI标识: 10.1016/j.phytochem.2012.06.013
语种: 英语
收录类别: SCI ; IC
学科分类: Biochemistry & Molecular Biology; Plant Sciences
ISSN号: 0031-9422
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/15934
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

Recommended Citation:
Cai, Xiang-Hai; Li, Yan; Liu, Ya-Ping; Li, Xiao-Ning; Bao, Mei-Fen; Luo, Xiao-Dong.Alkaloids from Melodinus yunnanensis,PHYTOCHEMISTRY,2012,83():116-124
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