Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi

doi:10.1055/s-0032-1315369

	Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi
	Cheng, Zhong-Quan 2,3; Yang, Dan 3; Ma, Qing-Yun 1; Dai, Hao-Fu 1; Huang, Sheng-Zhuo 1; Yi, Xiang-Hui 3; Zhou, Jun2 ; Zhao, You-Xing 1
通讯作者	Zhao,YX (reprint author), Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China.,751968889@qq.com
	2012-11-01
发表期刊	PLANTA MEDICA
ISSN	0032-0943
卷号	78 期号:17 页码:1878-1880
摘要	Three new sesquiterpenes dobinins A-C (1-3), together with five known compounds, were isolated from the root of Dobinea delavayi. The structures of the three new compounds were determined on the basis of spectroscopic analysis including 1D-, 2D-NMR and MS techniques as well as by comparison of the spectral data with those of analogous compounds reported in the literatures. Compounds 1-3 were screened for antitumor activity in vitro and exhibited definite cytotoxic activity against the human tumor cell line HL-60 with IC50 levels of 8.0 x 10(-5), 4.7 x 10(-5), and 5.1 x 10(-5) M, respectively.
关键词	Dobinea Delavayi Podoaceae Sesquiterpenes Anti-cancer Activity
学科领域	Plant Sciences ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
DOI	10.1055/s-0032-1315369
收录类别	SCI
语种	英语
WOS记录号	WOS:000311718900013
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/15920
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Guilin Normal Coll, Dept Chem & Engn, Guilin, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Zhong-Quan,Yang, Dan,Ma, Qing-Yun,et al. Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi[J]. PLANTA MEDICA,2012,78(17):1878-1880.
APA	Cheng, Zhong-Quan.,Yang, Dan.,Ma, Qing-Yun.,Dai, Hao-Fu.,Huang, Sheng-Zhuo.,...&Zhao, You-Xing.(2012).Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi.PLANTA MEDICA,78(17),1878-1880.
MLA	Cheng, Zhong-Quan,et al."Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi".PLANTA MEDICA 78.17(2012):1878-1880.

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