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Mycosphere Essays 7. Ganoderma lucidum - are the beneficial anti-cancer properties substantiated? 期刊论文
MYCOSPHERE, 2016, 卷号: 7, 期号: 3, 页码: 305-332
作者:  Hapuarachchi, K. K.;  Wen, T. C.;  Jeewon, R.;  Wu, X. L.;  Kang, J. C.;  Hyde, K. D.
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Anti-cancer Activity  Clinical Evidence  Ganoderma Lucidum  Lingzhi  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
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One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi 期刊论文
PLANTA MEDICA, 2012, 卷号: 78, 期号: 17, 页码: 1878-1880
作者:  Cheng, Zhong-Quan;  Yang, Dan;  Ma, Qing-Yun;  Dai, Hao-Fu;  Huang, Sheng-Zhuo;  Yi, Xiang-Hui;  Zhou, Jun;  Zhao, You-Xing
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Dobinea Delavayi  Podoaceae  Sesquiterpenes  Anti-cancer Activity