| Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi | |
Cheng, Zhong-Quan2,3; Yang, Dan3; Ma, Qing-Yun1; Dai, Hao-Fu1; Huang, Sheng-Zhuo1; Yi, Xiang-Hui3; Zhou, Jun2 ; Zhao, You-Xing1
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| 通讯作者 | Zhao,YX (reprint author), Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China.,751968889@qq.com |
| 2012-11-01 | |
| 发表期刊 | PLANTA MEDICA
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| ISSN | 0032-0943 |
| 卷号 | 78期号:17页码:1878-1880 |
| 摘要 | Three new sesquiterpenes dobinins A-C (1-3), together with five known compounds, were isolated from the root of Dobinea delavayi. The structures of the three new compounds were determined on the basis of spectroscopic analysis including 1D-, 2D-NMR and MS techniques as well as by comparison of the spectral data with those of analogous compounds reported in the literatures. Compounds 1-3 were screened for antitumor activity in vitro and exhibited definite cytotoxic activity against the human tumor cell line HL-60 with IC50 levels of 8.0 x 10(-5), 4.7 x 10(-5), and 5.1 x 10(-5) M, respectively. |
| 关键词 | Dobinea Delavayi Podoaceae Sesquiterpenes Anti-cancer Activity |
| 学科领域 | Plant Sciences ; Medicinal ; Chemistry ; Pharmacology & Pharmacy |
| DOI | 10.1055/s-0032-1315369 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000311718900013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/15920 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Guilin Normal Coll, Dept Chem & Engn, Guilin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cheng, Zhong-Quan,Yang, Dan,Ma, Qing-Yun,et al. Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi[J]. PLANTA MEDICA,2012,78(17):1878-1880. |
| APA | Cheng, Zhong-Quan.,Yang, Dan.,Ma, Qing-Yun.,Dai, Hao-Fu.,Huang, Sheng-Zhuo.,...&Zhao, You-Xing.(2012).Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi.PLANTA MEDICA,78(17),1878-1880. |
| MLA | Cheng, Zhong-Quan,et al."Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi".PLANTA MEDICA 78.17(2012):1878-1880. |
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