Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi
Cheng, Zhong-Quan2,3; Yang, Dan3; Ma, Qing-Yun1; Dai, Hao-Fu1; Huang, Sheng-Zhuo1; Yi, Xiang-Hui3; Zhou, Jun2; Zhao, You-Xing1
Corresponding AuthorZhao,YX (reprint author), Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China.,751968889@qq.com
2012-11-01
Source PublicationPLANTA MEDICA
ISSN0032-0943
Volume78Issue:17Pages:1878-1880
AbstractThree new sesquiterpenes dobinins A-C (1-3), together with five known compounds, were isolated from the root of Dobinea delavayi. The structures of the three new compounds were determined on the basis of spectroscopic analysis including 1D-, 2D-NMR and MS techniques as well as by comparison of the spectral data with those of analogous compounds reported in the literatures. Compounds 1-3 were screened for antitumor activity in vitro and exhibited definite cytotoxic activity against the human tumor cell line HL-60 with IC50 levels of 8.0 x 10(-5), 4.7 x 10(-5), and 5.1 x 10(-5) M, respectively.
KeywordDobinea Delavayi Podoaceae Sesquiterpenes Anti-cancer Activity
Subject AreaPlant Sciences ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
DOI10.1055/s-0032-1315369
Indexed BySCI
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000311718900013
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/15920
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Guilin Normal Coll, Dept Chem & Engn, Guilin, Peoples R China
Recommended Citation
GB/T 7714
Cheng, Zhong-Quan,Yang, Dan,Ma, Qing-Yun,et al. Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi[J]. PLANTA MEDICA,2012,78(17):1878-1880.
APA Cheng, Zhong-Quan.,Yang, Dan.,Ma, Qing-Yun.,Dai, Hao-Fu.,Huang, Sheng-Zhuo.,...&Zhao, You-Xing.(2012).Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi.PLANTA MEDICA,78(17),1878-1880.
MLA Cheng, Zhong-Quan,et al."Three New Sesquiterpenes with Cytotoxic Activity from Dobinea delavayi".PLANTA MEDICA 78.17(2012):1878-1880.
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