A new cadinane sesquiterpene with significant anti-HIV-1 activity from the cultures of the basidiomycete Tyromyces chioneus
Liu, Dong-Ze; Wang, Fei; Yang, Liu-Meng; Zheng, Yong-Tang; Liu, Ji-Kai
2007-05-01
发表期刊JOURNAL OF ANTIBIOTICS
ISSN0021-8820
卷号60期号:5页码:332-334
摘要A new cadinane sesquiterpene (4 beta,14-dihydroxy-6 alpha,7 beta H-1(10)-cadinene, 1) was isolated from the cultures of the basidiomycete, Tyromyces chioneus. Its structure was established on the basis of spectral measurements (MS, IR, 1D and 2D NMR experiments). 1 showed significant anti-HIV-1 activity with EC50,=3.0 mu g/ml (SI=25.4).
关键词Tyromyces Chioneus Culture Broth Cadinane Sesquiterpene Anti-hiv-1
学科领域Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
收录类别SCI ; IC
语种英语
WOS研究方向Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
WOS类目Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
WOS记录号WOS:000247117400007
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/1529
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming 650204, Peoples R China
2.Grad Univ, Chinese Acad Sci, Beijing 100049, Peoples R China
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Liu, Dong-Ze,Wang, Fei,Yang, Liu-Meng,et al. A new cadinane sesquiterpene with significant anti-HIV-1 activity from the cultures of the basidiomycete Tyromyces chioneus[J]. JOURNAL OF ANTIBIOTICS,2007,60(5):332-334.
APA Liu, Dong-Ze,Wang, Fei,Yang, Liu-Meng,Zheng, Yong-Tang,&Liu, Ji-Kai.(2007).A new cadinane sesquiterpene with significant anti-HIV-1 activity from the cultures of the basidiomycete Tyromyces chioneus.JOURNAL OF ANTIBIOTICS,60(5),332-334.
MLA Liu, Dong-Ze,et al."A new cadinane sesquiterpene with significant anti-HIV-1 activity from the cultures of the basidiomycete Tyromyces chioneus".JOURNAL OF ANTIBIOTICS 60.5(2007):332-334.
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