New Minor Spirostane Glycosides from Ypsilandra thibetica

doi:10.1002/hlca.201100368

	New Minor Spirostane Glycosides from Ypsilandra thibetica
	Zhang, Xu-Dong 1,2; Chen, Chang-Xiang1 ; Yang, Jun-Yun 1; Ni, Wei 1; Liu, Hai-Yang1
通讯作者	Liu, HY (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China. ; haiyangliu@mail.kib.ac.cn
	2012-07-01
发表期刊	HELVETICA CHIMICA ACTA
ISSN	0018-019X
卷号	95 期号:7 页码:1087-1093
摘要	A further phytochemical investigation on the whole plants of Ypsilandra thibetica yielded three new spirostane glycosides, named ypsilandrosides MO (13). Their structures were established as (3 beta,11a,25R)-3,11-dihydroxyspirost-5-en-12-one 3-{O-a-L-rhanmopyranosyl-(1?4)-O-L-rhanmopyranosyl-(1?4)-O-[a-L-rhanmopyranosyl-(1?2)]-beta-D-glucopyranoside} (1), (3 beta,7 beta,25R)-spirost-5-ene-3,7-diol 3-{O-a-L-rhanmopyranosyl-(1?4)-O-a-L-rhanmopyranosyl-(1?4)-O-[a-L-rhanmopyranosyl-(1?2)]-beta-D-glucopyranoside} (2), and (3 beta,7a,25R)-spirost-5-ene-3,7,17-triol 3-{O-a-L-rhanmopyranosyl-(1?4)-O-a-L-rhanmopyranosyl-(1?4)-O-[a-L-rhanmopyranosyl-(1?2)]-beta-D-glucopyranoside} (3) by means of a combination of MS, 1D- and 2D-NMR spectroscopic methods, and chemical degradation. Among them, compound 3 is the first pennogenin (=(3 beta,25R)-spirost-5-ene-3,17-diol) saponin whose aglycone contains an OH group at C(7). Compounds 13 were evaluated for the inhibition of the growth of five tumor cell lines, but all of them proved to be inactive.
关键词	Ypsilandra Thibetica YpsilandrM?-?osides m?-?M?-?o Spirostanes Glycosides
学科领域	Chemistry, Multidisciplinary
DOI	10.1002/hlca.201100368
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000306277000005
引用统计	被引频次：22[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/15091
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xu-Dong,Chen, Chang-Xiang,Yang, Jun-Yun,et al. New Minor Spirostane Glycosides from Ypsilandra thibetica[J]. HELVETICA CHIMICA ACTA,2012,95(7):1087-1093.
APA	Zhang, Xu-Dong,Chen, Chang-Xiang,Yang, Jun-Yun,Ni, Wei,&Liu, Hai-Yang.(2012).New Minor Spirostane Glycosides from Ypsilandra thibetica.HELVETICA CHIMICA ACTA,95(7),1087-1093.
MLA	Zhang, Xu-Dong,et al."New Minor Spirostane Glycosides from Ypsilandra thibetica".HELVETICA CHIMICA ACTA 95.7(2012):1087-1093.

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