Lanostane Triterpenoids from the Stems of Schisandra glaucescens
Zou, Juan1,2; Yang, Li-Bin1; Jiang, Jing3; Diao, Yan-Yan3; Li, Xiao-Nian1; Huang, Jin3; Yang, Jian-Hong1; Li, Hong-Lin3; Xiao, Wei-Lie1; Du, Xue1; Shang, Shan-Zhai1,2; Pu, Jian-Xin1; Sun, Han-Dong1
Corresponding AuthorSun, HD (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Lanhei Rd 132, Kunming 650201, Peoples R China, xwl@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
2012-03-01
Source PublicationPLANTA MEDICA
ISSN0032-0943
Volume78Issue:5Pages:472-479
AbstractTen new triterpenoids, schiglausins A-J (1-10), as well as four known compounds, were isolated from the stems of Schisandra glaucescens. Their structures were elucidated on the basis of spectroscopic methods, including extensive NMR spectra and CD experiment. Compound 8 was determined to be a norlanostane triterpenoid. The crystal structure of compound 1 has been determined using single-crystal X-ray analysis while its absolute configuration was assigned on the basis of the CD spectrum. All isolates were tested for their FXR agonistic and antagonistic effects.
KeywordLanostane Triterpenoids Schisandraceae Schisandra Glaucescens Fxr
Subject AreaPlant Sciences ; Medicinal ; Chemistry ; Pharmacology & Pharmacy
DOI10.1055/s-0031-1298214
Indexed BySCI
Language英语
WOS IDWOS:000302397400011
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/14983
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
3.E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China
Recommended Citation
GB/T 7714
Zou, Juan,Yang, Li-Bin,Jiang, Jing,et al. Lanostane Triterpenoids from the Stems of Schisandra glaucescens[J]. PLANTA MEDICA,2012,78(5):472-479.
APA Zou, Juan.,Yang, Li-Bin.,Jiang, Jing.,Diao, Yan-Yan.,Li, Xiao-Nian.,...&Sun, Han-Dong.(2012).Lanostane Triterpenoids from the Stems of Schisandra glaucescens.PLANTA MEDICA,78(5),472-479.
MLA Zou, Juan,et al."Lanostane Triterpenoids from the Stems of Schisandra glaucescens".PLANTA MEDICA 78.5(2012):472-479.
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