Lanostane Triterpenoids from the Stems of Schisandra glaucescens
Zou, Juan1,2; Yang, Li-Bin1; Jiang, Jing3; Diao, Yan-Yan3; Li, Xiao-Nian1; Huang, Jin3; Yang, Jian-Hong1; Li, Hong-Lin3; Xiao, Wei-Lie1; Du, Xue1; Shang, Shan-Zhai1,2; Pu, Jian-Xin1; Sun, Han-Dong1
2012-03-01
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号78期号:5页码:472-479
摘要Ten new triterpenoids, schiglausins A-J (1-10), as well as four known compounds, were isolated from the stems of Schisandra glaucescens. Their structures were elucidated on the basis of spectroscopic methods, including extensive NMR spectra and CD experiment. Compound 8 was determined to be a norlanostane triterpenoid. The crystal structure of compound 1 has been determined using single-crystal X-ray analysis while its absolute configuration was assigned on the basis of the CD spectrum. All isolates were tested for their FXR agonistic and antagonistic effects.
关键词Lanostane Triterpenoids Schisandraceae Schisandra Glaucescens Fxr
资助信息This project was supported financially by the NSFC (No. 20802082 and 30830115), Chinese Academy of Sciences (projects KSCX2-EW-Q-10 and KSCX1-YW-R-24), Major State Basic Research Development Program of China (No. 2009CB522303 and 2009CB940900), Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), and Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China (awarded to Dr. Hong-Lin Li).
收录类别SCI
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14983
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
3.E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China
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Zou, Juan,Yang, Li-Bin,Jiang, Jing,et al. Lanostane Triterpenoids from the Stems of Schisandra glaucescens[J]. PLANTA MEDICA,2012,78(5):472-479.
APA Zou, Juan.,Yang, Li-Bin.,Jiang, Jing.,Diao, Yan-Yan.,Li, Xiao-Nian.,...&Sun, Han-Dong.(2012).Lanostane Triterpenoids from the Stems of Schisandra glaucescens.PLANTA MEDICA,78(5),472-479.
MLA Zou, Juan,et al."Lanostane Triterpenoids from the Stems of Schisandra glaucescens".PLANTA MEDICA 78.5(2012):472-479.
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