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题名: Lanostane Triterpenoids from the Stems of Schisandra glaucescens
作者: Zou, Juan1, 2; Yang, Li-Bin1; Jiang, Jing3; Diao, Yan-Yan3; Li, Xiao-Nian1; Huang, Jin3; Yang, Jian-Hong1; Li, Hong-Lin3; Xiao, Wei-Lie1; Du, Xue1; Shang, Shan-Zhai1, 2; Pu, Jian-Xin1; null(孙汉董)1
刊名: PLANTA MEDICA
关键词: lanostane triterpenoids ; Schisandraceae ; Schisandra glaucescens ; FXR
英文摘要: Ten new triterpenoids, schiglausins A-J (1-10), as well as four known compounds, were isolated from the stems of Schisandra glaucescens. Their structures were elucidated on the basis of spectroscopic methods, including extensive NMR spectra and CD experiment. Compound 8 was determined to be a norlanostane triterpenoid. The crystal structure of compound 1 has been determined using single-crystal X-ray analysis while its absolute configuration was assigned on the basis of the CD spectrum. All isolates were tested for their FXR agonistic and antagonistic effects.
出版日期: 2012-03-01
卷号: 78, 期号:5, 页码:472-479
语种: 英语
收录类别: SCI
学科分类: Plant Sciences; Chemistry ; Medicinal; Pharmacology & Pharmacy
ISSN号: 0032-0943
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/14983
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
3.E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

Recommended Citation:
Zou, Juan; Yang, Li-Bin; Jiang, Jing; Diao, Yan-Yan; Li, Xiao-Nian; Huang, Jin; Yang, Jian-Hong; Li, Hong-Lin; Xiao, Wei-Lie; Du, Xue; Shang, Shan-Zhai; Pu, Jian-Xin; Sun, Han-Dong.Lanostane Triterpenoids from the Stems of Schisandra glaucescens,PLANTA MEDICA,2012,78(5):472-479
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