A New Cyclooxygenase Inhibitor from Incarvillea arguta
Tan, Qin-Gang1,2; Cai, Xiang-Hai1; Feng, Tao1,2; Du, Zhi-Zhi1; Luo, Xiao-Dong1
2009-04-01
发表期刊ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
ISSN0932-0776
卷号64期号:4页码:439-442
摘要A new anti-inflammatory spirovetivane-type sesquiterpenoid, designated as 1,10-didehydrolubimin (1) and thirteen known compounds (2-14) were isolated from the whole plants of the 'Yi' ethno-medicinal plant Incarvillea arguta. Their structures were established based oil spectral methods and by comparison of the spectral data with those reported previously. Compound I exhibited significant inhibitory effects oil Cox-1 and Cox-2 and a negative effect against 5-Lox at the concentration of 100 mu M.
关键词Incarvellea Arguta Bignoniaceac Cyclooxygenase Inhibitor 1 10-didehydrolubimin
学科领域Chemistry, Inorganic & Nuclear ; Chemistry, Organic
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Inorganic & Nuclear ; Chemistry, Organic
WOS记录号WOS:000265634500014
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14413
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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Tan, Qin-Gang,Cai, Xiang-Hai,Feng, Tao,et al. A New Cyclooxygenase Inhibitor from Incarvillea arguta[J]. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,2009,64(4):439-442.
APA Tan, Qin-Gang,Cai, Xiang-Hai,Feng, Tao,Du, Zhi-Zhi,&Luo, Xiao-Dong.(2009).A New Cyclooxygenase Inhibitor from Incarvillea arguta.ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,64(4),439-442.
MLA Tan, Qin-Gang,et al."A New Cyclooxygenase Inhibitor from Incarvillea arguta".ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES 64.4(2009):439-442.
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