Novel Alkaloids from Alstonia scholaris
Cai, Xiang-Hai1; Shang, Jian-Hua2; Feng, Tao1; Luo, Xiao-Dong1
2010-09-01
发表期刊ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
ISSN0932-0776
卷号65期号:9页码:1164-1168
摘要The alkaloidal fraction of Alstonia scholaris leaves shows anti inflammatory and analgesic bioactivity in two A phytochemical study on this fraction led to the isolation of two novel alkaloids scholarisine I and (+/-)-scholarisine II Their structures were elucidated on the basis of spectroscopic methods and a possible biogenesis is proposed (+/-) Scholarisine II selectively inhibited the inducible COX-2 rather than COX-1 and also markedly inhibited 5-LOX comparable to positive controls
关键词Alstonia Scholaris Scholarisines i And Ii Cox 5 Lox
学科领域Chemistry, Inorganic & Nuclear ; Chemistry, Organic
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Inorganic & Nuclear ; Chemistry, Organic
WOS记录号WOS:000284300500018
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/14407
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources, W China Kunming Inst Bot, Kunming 650204, Yunana, Peoples R China
2.Yunnan Inst Med Mat, Kunming 650111, Peoples R China
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Cai, Xiang-Hai,Shang, Jian-Hua,Feng, Tao,et al. Novel Alkaloids from Alstonia scholaris[J]. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,2010,65(9):1164-1168.
APA Cai, Xiang-Hai,Shang, Jian-Hua,Feng, Tao,&Luo, Xiao-Dong.(2010).Novel Alkaloids from Alstonia scholaris.ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,65(9),1164-1168.
MLA Cai, Xiang-Hai,et al."Novel Alkaloids from Alstonia scholaris".ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES 65.9(2010):1164-1168.
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