Three New Terpenoid Indole Alkaloids from Catharanthus roseus
Wang, Lei1,2; Zhang, Yu1; He, Hong-Ping1; Zhang, Qiang1; Li, Shi-Fei1,2; Hao, Xiao-Jiang1
2011-05-01
发表期刊PLANTA MEDICA
ISSN0032-0943
卷号77期号:7页码:754-758
摘要Three new terpenoid indole alkaloids, vidolicine (1), normacusine B N-oxide (2), and lochnerine N-oxide (3), together with seven known ones (410), were isolated from whole plants of Catharanthus roseus. Their structures were elucidated by spectroscopic methods (NMR, MS, UV, and IR). Cytotoxic activities of these isolates (1-10) were evaluated, but only compound 8 was active against HL-60, SMMC-7721, and A549 cell lines.
关键词Catharanthus Roseus (L.) G. Don Apocynaceae Terpenoid Indole Alkaloids Vidolicine Normacusine b N-oxide Lochnerine N-oxide Cytotoxic Activity
资助信息Ministry of Science and Technology[2009CB940900, 2009CB522300]; National Natural Science Foundation of China[30830114]
收录类别SCI
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/13563
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
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Wang, Lei,Zhang, Yu,He, Hong-Ping,et al. Three New Terpenoid Indole Alkaloids from Catharanthus roseus[J]. PLANTA MEDICA,2011,77(7):754-758.
APA Wang, Lei,Zhang, Yu,He, Hong-Ping,Zhang, Qiang,Li, Shi-Fei,&Hao, Xiao-Jiang.(2011).Three New Terpenoid Indole Alkaloids from Catharanthus roseus.PLANTA MEDICA,77(7),754-758.
MLA Wang, Lei,et al."Three New Terpenoid Indole Alkaloids from Catharanthus roseus".PLANTA MEDICA 77.7(2011):754-758.
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