| New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora | |
Wang, Wei-Guang1,2; Du, Xue1; Li, Xiao-Nian1; Wu, Hai-Yan1; Liu, Xu1; Shang, Shan-Zhai1,2; Zhan, Rui1,2; Liang, Cheng-Gin1,2; Kong, Ling-Mei1,2; Li, Yan1 ; Pu, Jian-Xin1; Sun, Han-Dong1
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| 通讯作者 | Pu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China, pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn |
| 2012-01-06 | |
| 发表期刊 | ORGANIC LETTERS
 |
| ISSN | 1523-7060 |
| 卷号 | 14期号:1页码:302-305 |
| 摘要 | Neolaxiflorin A (1), an unprecedented ent-kaurane diterpenoid with a bicyclo[3.1.0]hexane unit, and its seco-derivative, neolaxiflorin B (2), along with two known compounds 3 and 4 were isolated from the leaves of Isodon erlocalyx var. laxiflora. The absolute configuration of 1 was determined by spectral methods and single crystal X-ray diffraction analysis. Compound 4 and the synthesized compound 5 exhibited significant cytotoxicity. |
| 关键词 | Synthesis Caudatin Derivatives Anti-hbv Activity Structure-activity Relationships In-vitro Hbv Inhibitors Infection Alisol |
| 学科领域 | Chemistry ; Organic |
| DOI | 10.1021/ol203061z |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000298828500078 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/10437 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Wei-Guang,Du, Xue,Li, Xiao-Nian,et al. New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora[J]. ORGANIC LETTERS,2012,14(1):302-305. |
| APA | Wang, Wei-Guang.,Du, Xue.,Li, Xiao-Nian.,Wu, Hai-Yan.,Liu, Xu.,...&Sun, Han-Dong.(2012).New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora.ORGANIC LETTERS,14(1),302-305. |
| MLA | Wang, Wei-Guang,et al."New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora".ORGANIC LETTERS 14.1(2012):302-305. |
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