New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora
Wang, Wei-Guang1,2; Du, Xue1; Li, Xiao-Nian1; Wu, Hai-Yan1; Liu, Xu1; Shang, Shan-Zhai1,2; Zhan, Rui1,2; Liang, Cheng-Gin1,2; Kong, Ling-Mei1,2; Li, Yan1; Pu, Jian-Xin1; Sun, Han-Dong1
Corresponding AuthorPu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China, pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
2012-01-06
Source PublicationORGANIC LETTERS
ISSN1523-7060
Volume14Issue:1Pages:302-305
AbstractNeolaxiflorin A (1), an unprecedented ent-kaurane diterpenoid with a bicyclo[3.1.0]hexane unit, and its seco-derivative, neolaxiflorin B (2), along with two known compounds 3 and 4 were isolated from the leaves of Isodon erlocalyx var. laxiflora. The absolute configuration of 1 was determined by spectral methods and single crystal X-ray diffraction analysis. Compound 4 and the synthesized compound 5 exhibited significant cytotoxicity.
KeywordSynthesis Caudatin Derivatives Anti-hbv Activity Structure-activity Relationships In-vitro Hbv Inhibitors Infection Alisol
Subject AreaChemistry ; Organic
DOI10.1021/ol203061z
Indexed BySCI ; IC
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Organic
WOS IDWOS:000298828500078
Citation statistics
Cited Times:28[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/10437
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Wang, Wei-Guang,Du, Xue,Li, Xiao-Nian,et al. New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora[J]. ORGANIC LETTERS,2012,14(1):302-305.
APA Wang, Wei-Guang.,Du, Xue.,Li, Xiao-Nian.,Wu, Hai-Yan.,Liu, Xu.,...&Sun, Han-Dong.(2012).New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora.ORGANIC LETTERS,14(1),302-305.
MLA Wang, Wei-Guang,et al."New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora".ORGANIC LETTERS 14.1(2012):302-305.
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