| Indole alkaloids from Ervatamia chinensis | |
Guo, Ling-Li1,2 ; He, Hong-Ping1; Di, Ying-Tong1; Li, Shi-Fei1; Cheng, Yuan-Yuan1; Yang, Wei1; Li, Yan1; Yu, Jian-Ping2; Zhang, Yu1; Hao, Xiao-Jiang1
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| 通讯作者 | Zhang, Y (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China, zhangyu@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
| 2012-02-01 | |
| 发表期刊 | PHYTOCHEMISTRY
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| ISSN | 0031-9422 |
| 卷号 | 74页码:140-145 |
| 摘要 | Four vobasinyl-ibogan type bisindole alkaloids, ervachinines A-D (1-4), along with 12 known terpenoid indole alkaloids, were isolated from the whole plant of Ervatamia chinensis. Their structures were elucidated by analysis of spectroscopic data, including 1D and 2D NMR, and the absolute configurations of 1-4 were determined by CD exciton chirality method. All of the compounds were evaluated for in vitro cytotoxicity against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480. Bisindole alkaloids 1-6 exhibited inhibitory effects, with IC50 values comparable to those of cisplatin. (C) 2011 Elsevier Ltd. All rights reserved. |
| 关键词 | Ervatamia Chinensis Apocynaceae Bisindole Alkaloids Ervachinines A-d Cytotoxicity |
| 学科领域 | Biochemistry & Molecular Biology ; Plant Sciences |
| DOI | 10.1016/j.phytochem.2011.11.002 |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000300815700015 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/10369 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Guizhou Univ, Coll Life Sci, Guiyang 550025, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, Ling-Li,He, Hong-Ping,Di, Ying-Tong,et al. Indole alkaloids from Ervatamia chinensis[J]. PHYTOCHEMISTRY,2012,74:140-145. |
| APA | Guo, Ling-Li.,He, Hong-Ping.,Di, Ying-Tong.,Li, Shi-Fei.,Cheng, Yuan-Yuan.,...&Hao, Xiao-Jiang.(2012).Indole alkaloids from Ervatamia chinensis.PHYTOCHEMISTRY,74,140-145. |
| MLA | Guo, Ling-Li,et al."Indole alkaloids from Ervatamia chinensis".PHYTOCHEMISTRY 74(2012):140-145. |
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