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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
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2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 21, 页码: 4926-4930
作者:  Xu, Xiao-Liang;  Wang, Jia;  Yu, Chun-Lei;  Chen, Wen;  Li, Ying-Chao;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
Adobe PDF(670Kb)  |  收藏  |  浏览/下载:359/85  |  提交时间:2014/11/25
Indole  Imidazolium Salts  Structure-activity Relationships  Cell Apoptosis  
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载:292/72  |  提交时间:2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
New chlamydosporol derivatives from the endophytic fungus Fusarium sp #001 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2014, 卷号: 16, 期号: 5, 页码: 465-470
作者:  Chen, Zi-Ming;  Dong, Wen-Bin;  Li, Zheng-Hui;  Feng, Tao;  Liu, Ji-Kai
Adobe PDF(149Kb)  |  收藏  |  浏览/下载:226/52  |  提交时间:2014/06/23
Endophytic Fungi  Cytotoxicity  Fusarium Sp  Eupatorium Adenophorum  Chlamydosporol Derivatives  
Cytotoxic Amides and Quinolones from Clausena lansium 期刊论文
HELVETICA CHIMICA ACTA, 2014, 卷号: 97, 期号: 2, 页码: 298-305
作者:  Song, Wei-Wu;  Zeng, Guang-Zhi;  Peng, Wen-Wen;  Chen, Ke-Xian;  Tan, Ning-Hua
Adobe PDF(352Kb)  |  收藏  |  浏览/下载:269/64  |  提交时间:2014/05/16
Quinolones  Clausena Lansium  Cytotoxic Activity  Claulansamides a And b  Amides  
(+/-)-Paeoveitol, a Pair of New Norditerpene Enantiomers from Paeonia veitchii 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 2, 页码: 424-427
作者:  Liang, Wen-Juan;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Hao;  Yang, Cai-Yan;  Rong, Guang-Qing;  Zhao, Yong;  Xu, Hong-Bo;  Wang, Hao;  Zhou, Ning-Jia;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Chen, Ji-Jun
Adobe PDF(256Kb)  |  收藏  |  浏览/下载:364/128  |  提交时间:2014/04/09
Monoterpene Glycosides  Paeoniflorin  Root  
Four new sesquiterpenoids from fruiting bodies of the fungus Inonotus rickii 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2014, 卷号: 16, 期号: 6, 页码: 581-586
作者:  Chen, He-Ping;  Dong, Wen-Bin;  Feng, Tao;  Yin, Xia;  Li, Zheng-Hui;  Dong, Ze-Jun;  Li, Yan;  Liu, Ji-Kai;  Liu, JK (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China.;  jkliu@mail.kib.ac.cn
Adobe PDF(161Kb)  |  收藏  |  浏览/下载:220/64  |  提交时间:2014/10/11
Inonotus Rickii  Sesquiterpenoid  Cytotoxicity  
Synthesis and antitumor activities of novel dibenzo[b,d]furan-imidazole hybrid compounds 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 66, 页码: 423-437
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Yan, Ju-Ming;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Zhou, Bei;  Zhang, Hong-Bin;  Yang, Xiao-Dong
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Hybrid Compound  Imidazole  Dibenzo[b  Antitumor Activities  d]Furan  Structure-activity Relationships  
Synthesis and cytotoxic activities of novel hybrid 2-phenyl-3-alkylbenzofuran and imidazole/triazole compounds 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 15, 页码: 4297-4302
作者:  Chen, Wen;  Deng, Xiao-Yan;  Li, Yan;  Yang, Li-Juan;  Wan, Wei-Chao;  Wang, Xue-Quan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
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Hybrid Compound  Benzofuran  Imidazole  Triazole  Structure-activity Relationships  
Swerpunilactones A and B, the first example of xanthone and secoiridoid heterodimers from Swertia punicea, S. hispidicalyx, and S. yunnanensis 期刊论文
TETRAHEDRON LETTERS, 2013, 卷号: 54, 期号: 21, 页码: 2710-2712
作者:  Wang, Hong-Ling;  Cao, Tuan-Wu;  Jiang, Fu-Qiang;  Geng, Chang-An;  Zhang, Xue-Mei;  Huang, Xiao-Yan;  Wang, Li-Jun;  Kang-He, Sing Wd;  Hao-Chen;  Liang, Wen-Juan;  Rong, Guang-Qing;  Chen, Ji-Jun
浏览  |  Adobe PDF(393Kb)  |  收藏  |  浏览/下载:480/135  |  提交时间:2013/06/08
Swerpunilactones A-b  Anti-hbv Activity  Swertia Punicea  Swertia Hispidicalyx  Swertia Yunnanensis