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Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载:301/72  |  提交时间:2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Swerpunilactones A and B, the first example of xanthone and secoiridoid heterodimers from Swertia punicea, S. hispidicalyx, and S. yunnanensis 期刊论文
TETRAHEDRON LETTERS, 2013, 卷号: 54, 期号: 21, 页码: 2710-2712
作者:  Wang, Hong-Ling;  Cao, Tuan-Wu;  Jiang, Fu-Qiang;  Geng, Chang-An;  Zhang, Xue-Mei;  Huang, Xiao-Yan;  Wang, Li-Jun;  Kang-He, Sing Wd;  Hao-Chen;  Liang, Wen-Juan;  Rong, Guang-Qing;  Chen, Ji-Jun
Adobe PDF(393Kb)  |  收藏  |  浏览/下载:495/139  |  提交时间:2013/06/08
Swerpunilactones A-b  Anti-hbv Activity  Swertia Punicea  Swertia Hispidicalyx  Swertia Yunnanensis  
Synthesis of hemslecin A derivatives: A new class of hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 5, 页码: 1201-1205
作者:  Guo, Rui-Hua;  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Quan;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhang, Rong-Ping;  Chen, Ji-Jun
Adobe PDF(460Kb)  |  收藏  |  浏览/下载:393/93  |  提交时间:2013/03/18
Hemslecin a  Derivatives  Hepatitis b Virus  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(719Kb)  |  收藏  |  浏览/下载:430/138  |  提交时间:2012/11/30
Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms  
Anti-Hepatitis B Virus Active Lactones from the Traditional Chinese Herb: Swertia mileensis 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 卷号: 17, 期号: 14, 页码: 3893-3903
作者:  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Luo, Jie;  Guo, Rui-Hua;  Zhou, Jun;  Shen, Yong;  Zuo, Ai-Xue;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:397/126  |  提交时间:2012/04/10
Antiviral Agents  Biosynthesis  Fused-ring Systems  Hepatitis b Virus  Natural Products  Swerilactones H-k  Swertia Mileensis  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载:357/91  |  提交时间:2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships  
Two new sesquiterpenes from Alisma orientalis 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 卷号: 55, 期号: 6, 页码: 905-907
作者:  Jiang, Zhi-Yong;  Zhang, Xue-Mei;  Zhou, Jun;  Zhang, Feng-Xue;  Chen, Ji-Jun;  Lue, Yang;  Wu, Li;  Zheng, Qi-Tai
Adobe PDF(118Kb)  |  收藏  |  浏览/下载:339/137  |  提交时间:2011/11/24
Alisma Orientalis  Sesquiterpenoid  Alismorientol a  Alismorientol b  Anti-hepatitis b Virus Activity