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Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113794
作者:  Bao,Mei-Fen;  Yang,Xin-Ni;  Wu,Jing;  Liu,Jiang-Xin;  Cai,Xiang-Hai
浏览  |  Adobe PDF(3069Kb)  |  收藏  |  浏览/下载：17/3  |  提交时间：2024/07/25
Dactylicapnos scandens (D. don) hutch.  Isoquinoline alkaloids  Aporphine-type alkaloids  Dactycapnine a  IDO1/TDO dual inhibitor  APORPHINE ALKALOIDS  N-OXIDE  INFLAMMATION  PATHWAY  THALIPORPHINE  COMPLEXES  CANCER  ROOTS  
Prophylactic Effects of Bifidobacterium adolescentis on Anxiety and Depression-Like Phenotypes After Chronic Stress: A Role of the Gut Microbiota-Inflammation Axis 期刊论文
FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 2019, 卷号: 13, 页码: 17
作者:  Guo, Ying;  Xie, Jian-Ping;  Deng, Ke;  Li, Xia;  Yuan, Yun;  Xuan, Qun;  Xie, Jing;  He, Xiao-Ming;  Wang, Qian;  Li, Juan-Juan;  Luo, Huai-Rong
浏览  |  Adobe PDF(4609Kb)  |  收藏  |  浏览/下载：226/29  |  提交时间：2019/07/29
Bifidobacterium adolescentis  antidepressant  chronic restraint stress  gut microbiota  inflammation  
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(2732Kb)  |  收藏  |  浏览/下载：286/47  |  提交时间：2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS