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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：328/74  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 21, 页码: 4926-4930
作者:  Xu, Xiao-Liang;  Wang, Jia;  Yu, Chun-Lei;  Chen, Wen;  Li, Ying-Chao;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
Adobe PDF(670Kb)  |  收藏  |  浏览/下载：376/89  |  提交时间：2014/11/25
Indole  Imidazolium Salts  Structure-activity Relationships  Cell Apoptosis  
Synthesis and antitumor activities of novel dibenzo[b,d]furan-imidazole hybrid compounds 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 66, 页码: 423-437
作者:  Liu, Lan-Xiang;  Wang, Xue-Quan;  Yan, Ju-Ming;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Zhou, Bei;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(3339Kb)  |  收藏  |  浏览/下载：332/141  |  提交时间：2013/10/16
Hybrid Compound  Imidazole  Dibenzo[b  Antitumor Activities  d]Furan  Structure-activity Relationships  
Synthesis and cytotoxic activities of novel hybrid 2-phenyl-3-alkylbenzofuran and imidazole/triazole compounds 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 15, 页码: 4297-4302
作者:  Chen, Wen;  Deng, Xiao-Yan;  Li, Yan;  Yang, Li-Juan;  Wan, Wei-Chao;  Wang, Xue-Quan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(820Kb)  |  收藏  |  浏览/下载：245/45  |  提交时间：2013/10/16
Hybrid Compound  Benzofuran  Imidazole  Triazole  Structure-activity Relationships  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
Adobe PDF(531Kb)  |  收藏  |  浏览/下载：303/63  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Design, synthesis and biological evaluation of novel hybrid compounds of imidazole scaffold-based 2-benzylbenzofuran as potent anticancer agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 62, 页码: 111-121
作者:  Wang, Xue-Quan;  Liu, Lan-Xiang;  Li, Yan;  Sun, Cheng-Jun;  Chen, Wen;  Li, Liang;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(4369Kb)  |  收藏  |  浏览/下载：291/96  |  提交时间：2013/07/24
Hybrid Compound  2-benzylbenzofuran  Imidazole  Cytotoxic Activities  Structure-activity Relationships  
Cycloartane triterpenoids from the aerial parts of Cimicifuga foetida Linnaeus 期刊论文
PHYTOCHEMISTRY, 2011, 卷号: 72, 期号: 11-12, 页码: 1473-1481
作者:  Nian, Yin;  Zhang, Xian-Min;  Li, Yan;  Wang, Yuan-Yuan;  Chen, Jian-Chao;  Lu, Lu;  Zhou, Lin;  Qiu, Ming-Hua
Adobe PDF(368Kb)  |  收藏  |  浏览/下载：531/168  |  提交时间：2012/04/10
Cimicifuga Foetida  Ranunculaceae  Cycloartane Triterpenoids  Cytotoxicity  Structure-activity Relationships  
Microbial transformation of diosgenin by filamentous fungus Cunninghamella echinulata 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2011, 卷号: 13, 期号: 3, 页码: 270-275
作者:  Xiao, Xiao;  Liu, Xi-Kui;  Fu, Shao-Bin;  Sun, Di-An
Adobe PDF(97Kb)  |  收藏  |  浏览/下载：262/111  |  提交时间：2012/04/10
Microbial Transformation  Biotransformation  Hydroxylation  Diosgenin Cunninghamella Echinulata Cgmcc 3  2000  
Novel ceramides from the fungus Lactarium volemus 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2001, 卷号: 64, 期号: 9, 页码: 1246-1248
作者:  Yue, JM;  Fan, CQ;  Xu, J;  Sun, HD
Adobe PDF(38Kb)  |  收藏  |  浏览/下载：202/102  |  提交时间：2012/03/21
Antineoplastic Agents  Norbisabolane  Glycosides  Tannins  Acid