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The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
作者:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：491/1  |  提交时间：2017/07/24
The dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2-dependent and -independent fever while 4-AA only blocks PGE2-dependent fever1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  David do C. Malvar;  Fernando A. Aguiar;  Artur de L. L. Vaz;  Débora C. R. Assis;  Miriam C. C. de Melo;  Valquíria A. P. Jabor;  Evanguedes Kalapothakis;  Sérgio H. Ferreira;  Giuliano C. Clososki;  Glória E. P. de Souza
Adobe PDF(2243Kb)  |  收藏  |  浏览/下载：474/1  |  提交时间：2017/07/24
Dipyrone  Dipyrone Metabolites  Fever  Hypothermia  Lps  Tityus Serrulatus Venom  
Effects of CO-RM2 on LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  Pei-Ling Chi;  Yu-Chen Chuang;  Yu-Wen Chen;  Chih-Chung Lin;  Li-Der Hsiao;  Chuen-Mao Yang
Adobe PDF(1319Kb)  |  收藏  |  浏览/下载：320/1  |  提交时间：2017/07/24
Carbon Monoxide  Lipopolysaccharide  Vcam-1  Leukocyte Adhesion  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  收藏  |  浏览/下载：346/1  |  提交时间：2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
Novel Signature Genes and Pathways Identified for Human Left Ventricle Cardiomyopathies Rise from different Etiologies 期刊论文
Journal of Biomedical Research and Reviews, 2021
作者:  Jiao Tian;  Zheng Yuan Wu;  Ying Ying He;  Shubai Liu
浏览  |  Adobe PDF(1819Kb)  |  收藏  |  浏览/下载：163/59  |  提交时间：2023/09/08
High-quality genome assembly of an important biodiesel plant, Euphorbia lathyris L. 期刊论文
DNA RESEARCH, 2021, 卷号: 28, 期号: 6, 页码: dsab022
作者:  Wang,Mingcheng;  Gu,Zhijia;  Fu,Zhixi;  Jiang,Dechun
浏览  |  Adobe PDF(669Kb)  |  收藏  |  浏览/下载：258/85  |  提交时间：2022/04/02
caper spurge  biodiesel plant  genome assembly  nanopore sequencing  oil metabolism  PHYLOGENETIC ANALYSIS  FOSSIL-FUELS  ANNOTATION  TOOL  IDENTIFICATION  PREDICTION  DATABASE  SEEDS  GENE  
Adaptive innovation of green plants by horizontal gene transfer 期刊论文
BIOTECHNOLOGY ADVANCES, 2021, 卷号: 46, 页码: 107671
作者:  Chen,Rujia;  Huangfu,Liexiang;  Lu,Yue;  Fang,Huimin;  Xu,Yang;  Li,Pengcheng;  Zhou,Yong;  Xu,Chenwu;  Huang,Jinling;  Yang,Zefeng
浏览  |  Adobe PDF(8443Kb)  |  收藏  |  浏览/下载：342/86  |  提交时间：2022/04/02
Plant evolution  adaptation  exaptation  plant-to-plant HGT  crop breeding and improvement  ICE-BINDING PROTEINS  LAND PLANTS  TRANSPOSABLE ELEMENTS  EVOLUTION  GENOME  ORIGIN  DNA  BIOSYNTHESIS  ALGA  RETROTRANSPOSONS  
Discovery of novel modulators targeting human TRPC5: Docking-based virtual screening, molecular dynamics simulation and binding af fi nity predication 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2021, 卷号: 102, 页码: 107795
作者:  Liu,Bin;  Zhang,Wei;  Guo,Sheng;  Zuo,Zhili
浏览  |  Adobe PDF(4277Kb)  |  收藏  |  浏览/下载：212/26  |  提交时间：2022/04/02
hTRPC5  Homology modeling  Molecular docking  Molecular dynamics simulation  Virtual screening  INHIBITOR  CHANNELS  GROMACS  POTENT  AMBER  IDENTIFICATION  CONSTRAINTS  INTEGRATION  AMYGDALA  
Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer 期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 697
作者:  He,YingYing;  He,Zhicheng;  Zhang,Xiaoyu;  Liu,Shubai
浏览  |  Adobe PDF(2666Kb)  |  收藏  |  浏览/下载：206/38  |  提交时间：2022/04/02
Ovarian cancer  Ester lipid  Tyrosine kinase signaling pathway  Platelet-activating factor  FACTOR-ACETYLHYDROLASE ACTIVITY  LYSOPHOSPHATIDIC ACID  FACTOR RECEPTOR  EMERGING ROLE  EXPRESSION  GROWTH  PAF  MECHANISMS  PAFAH1B3  SUBUNIT  
Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans 期刊论文
CELL CALCIUM, 2021, 卷号: 93, 页码: 102327
作者:  Yang,Zhong-Lin;  Chen,Jian-Ning;  Lu,Yu-Yang;  Lu,Min;  Wan,Qin-Li;  Wu,Gui-Sheng;  Luo,Huai-Rong
浏览  |  Adobe PDF(4473Kb)  |  收藏  |  浏览/下载：301/95  |  提交时间：2022/04/02
Inositol polyphosphates  Inositol polyphosphate multikinase  Type I inositol 5-phosphatase  Development  Calcium signaling  Defecation rhythm  C. elegans  C-ELEGANS  PHOSPHOLIPASE-C  CALCIUM  1,4,5-TRISPHOSPHATE  CALCINEURIN  KINASE  IDENTIFICATION  TRISPHOSPHATE  METABOLISM  RECEPTOR