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Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载:280/47  |  提交时间:2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
Adobe PDF(1562Kb)  |  收藏  |  浏览/下载:297/45  |  提交时间:2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载:309/60  |  提交时间:2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Induction of leukemia cell apoptosis by cheliensisin A involves down-regulation of Bcl-2 expression 期刊论文
ACTA PHARMACOLOGICA SINICA, 2005, 卷号: 26, 期号: 5, 页码: 623-628
作者:  Zhong, L;  Li, CM;  Hao, XJ;  Lou, LG
Adobe PDF(6986Kb)  |  收藏  |  浏览/下载:135/28  |  提交时间:2012/07/25
Goniothalamus Cheliensis  Cheliensisin a  Apoptosis  Hl-60 Cells  Bcl-2 Genes  Cyclic Amp-dependent Protein Kinases  Caspases