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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：342/78  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 and stimulators of neural stem cell proliferation 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8852-8857
作者:  Tang, Jian-Jun ab;  Zhang, Li;  Jiang, Li-Ping;  Di, Lei;  Yan, Yong-Ming;  Tu, Zheng-Chao;  Yang, Cui-Ping;  Zuo, Zhi-Li;  Hou, Bo;  Xia, Hou-Lin;  Chen, Yong-Bin;  Cheng, Yong-Xian;  Tu,ZC (reprint author),Chinese Acad Sci,Guangzhou Inst Biomed & Hlth,Key Lab Regenerat Biol,Guangzhou 510530,Guangdong,Peoples R China.;  tu_zhengchao@gibh.ac.cn;  ybchen@mail.kiz.ac.cn;  yxcheng@mail.kib.ac.cn
浏览  |  Adobe PDF(678Kb)  |  收藏  |  浏览/下载：471/99  |  提交时间：2015/01/20
Polyrhachis Dives  Dopamine Derivative  Rock1/2 Inhibitors  Nscs  
Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 21, 页码: 4926-4930
作者:  Xu, Xiao-Liang;  Wang, Jia;  Yu, Chun-Lei;  Chen, Wen;  Li, Ying-Chao;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
Adobe PDF(670Kb)  |  收藏  |  浏览/下载：387/92  |  提交时间：2014/11/25
Indole  Imidazolium Salts  Structure-activity Relationships  Cell Apoptosis  
Multidrug resistance-selective antiproliferative activity of Piper amide alkaloids and synthetic analogues 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 20, 页码: 4818-4821
作者:  Wang, Yue-Hu;  Goto, Masuo;  Wang, Li-Ting;  Hsieh, Kan-Yen;  Morris-Natschke, Susan L.;  Tang, Gui-Hua;  Long, Chun-Lin;  Lee, Kuo-Hsiung;  Wang,YH (reprint author),Univ N Carolina,Eshelman Sch Pharm,Nat Prod Res Labs,Chapel Hill,NC 27599 USA.;  wangyuehu@mail.kib.ac.cn;  khlee@unc.edu
Adobe PDF(492Kb)  |  收藏  |  浏览/下载：304/71  |  提交时间：2014/11/25
Piper  Piperaceae  Amide Alkaloids  Cytotoxicity  Multidrug Resistance  
6,7-Seco-ent-kaurane-type diterpenoids from Isodon eriocalyx var. laxiflora 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 41, 页码: 7445-7453
作者:  Wang, Wei-Guang;  Yan, Bing-Chao;  Li, Xiao-Nian;  Du, Xue;  Wu, Hai-Yan;  Zhan, Rui;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(908Kb)  |  收藏  |  浏览/下载：306/94  |  提交时间：2014/11/25
Ent-kaurane  Diterpenoids  Isodon  
Synthesis and conformation studies of rubiyunnanin B analogs 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 37, 页码: 6630-6640
作者:  Liu, Na-Na;  Zhao, Si-Meng;  Zhao, Jing-Feng;  Zeng, Guang-Zhi;  Tan, Ning-Hua;  Liu, Jian-Ping;  Tan, NH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China.;  nhtan@mail.kib.ac.cn;  jpliu@ynu.edu.cn
Adobe PDF(619Kb)  |  收藏  |  浏览/下载：221/53  |  提交时间：2014/10/11
Rubiyunnanin b Analogs  Synthesis  Conformation Studies  Bioactivities  
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载：312/75  |  提交时间：2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Two new sesquiterpenoid glycosides from Nicotiana tabacum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2014, 卷号: 16, 期号: 6, 页码: 611-616
作者:  Yang, Cai-Yan;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Zhang, Xue-Mei;  Zhou, Jun;  Chen, Ji-Jun;  Chen, JJ (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China.;  chenjj@mail.kib.ac.cn
Adobe PDF(171Kb)  |  收藏  |  浏览/下载：239/63  |  提交时间：2014/10/11
Nicotabalactonecoside  Nicotabadiolcoside  Sesquiterpenoids  Nicotiana Tabacum  
Total synthesis of (+/-)-brazilin and formal synthesis of (+/-)-brazilein, (+/-)-brazilide A using m-CPBA 期刊论文
TETRAHEDRON LETTERS, 2013, 卷号: 54, 期号: 45, 页码: 6029-6031
作者:  Li, Liang-Qun;  Li, Ming-Ming;  Wang, Kou;  Qin, Hong-Bo
Adobe PDF(608Kb)  |  收藏  |  浏览/下载：630/133  |  提交时间：2013/11/12
Total Synthesis  Brazilin  Brazilein  Brazilide a  M-cpba  
Three new compounds from the cultures of basidiomycete Boreostereum vibrans 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2013, 卷号: 15, 期号: 9, 页码: 950-955
作者:  Wang, Gang-Qiang;  Wei, Kun;  Li, Zheng-Hui;  Feng, Tao;  Ding, Jian-Hai;  Wang, Qiu-An;  Liu, Ji-Kai
Adobe PDF(118Kb)  |  收藏  |  浏览/下载：237/64  |  提交时间：2014/01/13
Boreostereum Vibrans  Basidiomycete  Vibralactone Derivatives