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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway
期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:
Geng,Chang-An
;
Chen,Feng-Yang
;
Zheng,Jing-Bin
;
Liao,Ping
;
Li,Tian-Ze
;
Zhang,Xue-Mei
;
Chen,Xin
;
Chen,Ji-Jun
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浏览/下载:6/2
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提交时间:2024/07/17
Rubiginosin B (RGB)
CD4(+)Foxp3(+) regulatory T cells (Tregs)
Calcineurin
Nuclear factor of activated T cells (NFAT)
Tumor microenvironment
Rhododendron brachypodum
REGULATORY T-CELLS
RHODODENDRON
IMMUNOSUPPRESSION
DERIVATIVES
INDUCTION
EXPANSION
RAPAMYCIN
Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 11, 页码: 2045-2057
作者:
Li, Tian-Ze
;
Huang, Xiao-Yan
;
Sun, Jin-Jin
;
Geng, Chang-An
;
Zhang, Xue-Mei
;
Chen, Ji-Jun
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Adobe PDF(1234Kb)
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浏览/下载:42/10
  |  
提交时间:2024/04/30
(+)-Paeoveitol derivatives
Antidepressant
Forced swimming test
Monoamine neurotransmitter
Synthesis and biological evaluation of paeoveitol D derivatives as new melatonin receptor agonists with antidepressant activities
期刊论文
RSC MEDICINAL CHEMISTRY, 2022, 卷号: 13, 期号: 10, 页码: 1212-1224
作者:
Li, Tian-Ze
;
Hu, Jing
;
Sun, Jin-Jin
;
Huang, Xiao-Yan
;
Geng, Chang-An
;
Liu, Shu-Bai
;
Zhang, Xue-Mei
;
Chen, Ji-Jun
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Adobe PDF(932Kb)
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浏览/下载:43/12
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提交时间:2024/04/30
BENZOFURAN
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Li,Tian-Ze
;
Hu,Jing
;
Huang,Xiao-Yan
;
Zhang,Xue-Mei
;
Guo,Yuan-Qiang
;
Geng,Chang-An
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浏览/下载:147/62
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提交时间:2022/04/02
Alpinia katsumadai
Katsumadainols B-1-B-15
Natural products
Structure elucidation
Biological activity
TYROSINE-PHOSPHATASE 1B
GLYCOGEN-PHOSPHORYLASE
ALPHA-GLUCOSIDASE
ABSOLUTE-CONFIGURATION
STRUCTURE ELUCIDATION
DUAL INHIBITION
SEEDS
CONSTITUENT
DERIVATIVES
CHALCONE
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors
期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Huang,Xiao-Yan
;
Hu,Jing
;
Zhang,Xu-Ke
;
Guo,Yuan-Qiang
;
Zhang,Xue-Mei
;
Geng,Chang-An
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Adobe PDF(5184Kb)
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浏览/下载:100/28
  |  
提交时间:2022/04/02
Amomum tsao-ko
Amomutsaokins A-H
Flavanol-menthane conjugates
PTP1B selective inhibitors
alpha-Glucosidase inhibitors
ANTIOXIDANT ACTIVITY
ESSENTIAL OIL
CONSTITUENTS
TANNINS
CREVOST
ACID
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Li,Tian-Ze
;
Hu,Jing
;
Zhang,Xue-Mei
;
Geng,Chang-An
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Adobe PDF(2223Kb)
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浏览/下载:133/55
  |  
提交时间:2022/04/02
Alpinia katsumadai
Katsumadainols A(1)-A(16)
PTP1B/TCPTP selective inhibitors
alpha-glucosidase inhibitors
Antidiabetic effects
THEORETICAL CALCULATION
ABSOLUTE-CONFIGURATION
SEEDS
BLEPHAROCALYXINS
ADDUCT
MOIETY
Synthesis and anti-fibrotic effects of santamarin derivatives as cytotoxic agents against hepatic stellate cell line LX2
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 127994
作者:
Wang,Jin-Ping
;
Li,Tian-Ze
;
Huang,Xiao-Yan
;
Geng,Chang-An
;
Shen,Cheng
;
Sun,Jin-Jin
;
Xue,Dong
;
Chen,Ji-Jun
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Adobe PDF(567Kb)
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浏览/下载:99/36
  |  
提交时间:2022/04/02
Santamarin derivatives
Anti-fibrotic effects
HSC-LX2
Extracellular matrix
NF-KAPPA-B
SESQUITERPENE LACTONES
LIVER FIBROSIS
STRUCTURE REQUIREMENT
BAY LEAF
ACTIVATION
Abietane Diterpenoids with Antioxidative Damage Activity from Rosmarinus officinalis
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:
Chen, Xing-Long
;
Luo, Qing-Yi
;
Hu, Wei-Yan
;
Chen, Ji-Jun
;
Zhang, Rong-Ping
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Adobe PDF(1537Kb)
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浏览/下载:138/32
  |  
提交时间:2021/01/05
Cytotoxic sesquiterpenoids against hepatic stellate cell line LX2 from Artemisia lavandulaefolia
期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:
Shen, Cheng
;
Huang, Xiao-Yan
;
Geng, Chang-An
;
Li, Tian-Ze
;
Wang, Jin-Ping
;
Tang, Shuang
;
Su, Li-Hua
;
Gao, Zhen
;
Zhang, Xue-Mei
;
Chen, Ji-Jun
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  |  
Adobe PDF(2199Kb)
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浏览/下载:173/40
  |  
提交时间:2021/01/05
Amomutsaokols A-K, diarylheptanoids from Amomum tsao-ko and their alpha-glucosidase inhibitory activity
期刊论文
PHYTOCHEMISTRY, 2020
作者:
He, Xiao-Feng
;
Wang, Hui-Mei
;
Geng, Chang-An
;
Hu, Jing
;
Zhang, Xue-Mei
;
Guo, Yuan-Qiang
;
Chen, Ji-Jun
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Adobe PDF(3949Kb)
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  |  
浏览/下载:152/49
  |  
提交时间:2021/01/05