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Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
浏览  |  Adobe PDF(3665Kb)  |  收藏  |  浏览/下载:115/19  |  提交时间:2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer 期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 697
作者:  He,YingYing;  He,Zhicheng;  Zhang,Xiaoyu;  Liu,Shubai
浏览  |  Adobe PDF(2666Kb)  |  收藏  |  浏览/下载:110/23  |  提交时间:2022/04/02
Ovarian cancer  Ester lipid  Tyrosine kinase signaling pathway  Platelet-activating factor  FACTOR-ACETYLHYDROLASE ACTIVITY  LYSOPHOSPHATIDIC ACID  FACTOR RECEPTOR  EMERGING ROLE  EXPRESSION  GROWTH  PAF  MECHANISMS  PAFAH1B3  SUBUNIT  
Trichothecin Induces Cell Death in NF-kappa B Constitutively Activated Human Cancer Cells via Inhibition of IKK beta Phosphorylation 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e71333
作者:  Su, Jia;  Zhao, Peiji;  Kong, Lingmei;  Li, Xingyao;  Yan, Juming;  Zeng, Ying;  Li, Yan
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Colitis-associated Cancer  Multiple-myeloma Cells  P65 Phosphorylation  Endophytic Fungus  Kinase-activity  Tumor-growth  In-vitro  Pathway  Apoptosis  Inflammation  
Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 7, 页码: e21930
作者:  Liu, Ying;  Chen, Xiao-Qin;  Liang, Heng-Xing;  Zhang, Feng-Xiang;  Zhang, Bo;  Jin, Jie;  Chen, Yong-Long;  Cheng, Yong-Xian;  Zhou, Guang-Biao
Adobe PDF(877Kb)  |  收藏  |  浏览/下载:554/131  |  提交时间:2012/03/16
Nf-kappa-b  Cell-cycle Control  Overcomes Drug-resistance  Centipeda-minima  Antitumor-activity  Kinase-activity  Human Cancer  In-vitro  Activation  Expression