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ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载：112/18  |  提交时间：2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort 期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 34, 页码: 11438-11446
作者:  Guo,Yi;  Huang,Fang;  Sun,Weiguang;  Zhou,Yuan;  Chen,Chunmei;  Qi,Changxing;  Yang,Jing;  Li,Xiao-Nian;  Luo,Zengwei;  Zhu,Hucheng;  Wang,Xiaochuan;  Zhang,Yonghui
收藏  |  浏览/下载：192/0  |  提交时间：2022/04/02
AMYLOID-BETA  NEUROFIBRILLARY DEGENERATION  HYPERFORIN  NEUROTOXICITY  PATHOGENESIS  INHIBITION  BACE1  DRUG  TAU  
Comparative QSAR studies using HQSAR, CoMFA, and CoMSIA methods on cyclic sulfone hydroxyethylamines as BACE1 inhibitors 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 67, 期号: 1, 页码: 38-47
作者:  Zhang, Shuqun;  Lin, Zichun;  Pu, Yinglan;  Zhang, Yunqin;  Zhang, Li;  Zuo, Zhili
浏览  |  Adobe PDF(1591Kb)  |  收藏  |  浏览/下载：360/69  |  提交时间：2017/05/19
Bace1  Ad  Hqsar  Comfa  Comsia  
Four new fawcettimine-related alkaloids from Phlegmariurus squarrosus 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 卷号: 17, 期号: 10, 页码: 967-975
作者:  Liu,Yu-Chen;  Fan,Min;  Jiang,Wei-Wei;  Liu,Fei;  Wu,Xing-De;  He,Juan;  Cheng,Xiao;  Peng,Li-Yan;  Su,Jia;  Zhang,Zhi-Jun;  Zhao,Qin-Shi
浏览  |  Adobe PDF(591Kb)  |  收藏  |  浏览/下载：240/52  |  提交时间：2016/01/19
Fawcettimine-related Alkaloids  Phlegmariurus Squarrosus  Bace1 Inhibitory Activity  Ache Inhibitory Activity