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ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载：110/18  |  提交时间：2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Genome-wide analysis and prediction of genes involved in the biosynthesis of polysaccharides and bioactive secondary metabolites in high-temperature-tolerant wildFlammulina filiformis 期刊论文
BMC GENOMICS, 2020
作者:  Chen, Juan;  Li, Jia-Mei;  Tang, Yan-Jing;  Ma, Ke;  Li, Bing;  Zeng, Xu;  Liu, Xiao-Bin;  Li, Yang;  Yang, Zhu-Liang;  Xu, Wei-Nan;  Xie, Bao-Gui;  Liu, Hong-Wei;  Guo, Shun-Xing
浏览  |  Adobe PDF(1881Kb)  |  收藏  |  浏览/下载：253/125  |  提交时间：2021/01/05
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载：374/65  |  提交时间：2020/03/18
Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 6, 页码: 467-473
作者:  Sun Chang-Li;  Geng Chang-An;  Huang Xiao-Yan;  Ma Yun-Bao;  Zheng Xiao-Hong;  Yang Tong-Hua;  Chen Xing-Long;  Yin Xiu-Juan;  Zhang Xue-Mei;  Chen Ji-Jun
浏览  |  Adobe PDF(746Kb)  |  收藏  |  浏览/下载：317/106  |  提交时间：2017/10/23
Bupleurum Chinense  5-hydroxytryptamine 2c (5-ht2c) Receptor  Anti-obesity  Saikosaponins  
Catalytic Asymmetric Total Synthesis of (+)- and (-)-Paeoveitol via a Hetero-Diels-Alder Reaction 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 3, 页码: 429-431
作者:  Li,Tian-Ze;  Geng,Chang-An;  Yin,Xiu-Juan;  Yang,Tong-Hua;  Chen,Xing-Long;  Huang,Xiao-Yan;  Ma,Yun-Bao;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(553Kb)  |  收藏  |  浏览/下载：199/67  |  提交时间：2017/10/23
Ortho-quinone Methides  Paeonia-veitchii  Natural-products  Paeoveitol  
Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 6, 页码: 610-622
作者:  Yin, Xiu-Juan;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Geng, Chang-An;  Li, Tian-Ze;  Chen, Xing-Long;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2718Kb)  |  收藏  |  浏览/下载：388/73  |  提交时间：2017/07/10
Gramine  Melatonin Receptor  5-hydroxy-tryptamine Receptor  Agonistic Activity  Structure-activity Relationships  
Bioactivity-guided synthesis of tropine derivatives as new agonists for melatonin receptors 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 51, 页码: 45059-45063
作者:  Yin, Xiu-Juan;  Geng, Chang-An;  Huang, Xiao-Yan;  Chen, Hao;  Ma, Yun-Bao;  Chen, Xing-Long;  Sun, Chang-Li;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1380Kb)  |  收藏  |  浏览/下载：362/85  |  提交时间：2016/08/22
Vibsanin B Preferentially Targets HSP90b, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis 期刊论文
JOURNAL OF IMMUNOLOGY, 2015, 卷号: 194, 期号: 9, 页码: 4489-4497
作者:  Ye, Bai-Xin;  Deng, Xu;  Shao, Li-Dong;  Lu, Ying;  Xiao, Run;  Liu, Yi-Jie;  Jin, Yi;  Xie, Yin-Yin;  Zhao, Yan;  Luo, Liu-Fei;  Ma, Shun;  Gao, Ming;  Zhang, Lian-Ru;  He, Juan;  Zhang, Wei-Na;  Chen, Yi;  Xia, Cheng-Feng;  Deng, Min;  Liu, Ting-Xi;  Zhao, Qin-Shi;  Chen, Sai-Juan;  Chen, Zhu;  Chen,Z (reprint author),Shanghai Jiao Tong Univ,RuiJin Hosp,Sch Med,197 Rui Jin Rd 2,Shanghai 200025,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  sjchen@stn.sh.cn;  zchen@stn.sh.cn
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Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(3861Kb)  |  收藏  |  浏览/下载：356/82  |  提交时间：2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Preventive and Therapeutic Effects of Adenanthin on Experimental Autoimmune Encephalomyelitis by Inhibiting NF-kappa B Signaling 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 191, 期号: 5, 页码: 2115-2125
作者:  Yin, Qian-Qian;  Liu, Chuan-Xu;  Wu, Ying-Li;  Wu, Shao-Fang;  Wang, Yan;  Zhang, Xia;  Hu, Xiao-Juan;  Pu, Jian-Xin;  Lu, Ying;  Zhou, Hu-Chen;  Wang, Hong-Lin;  Nie, Hong;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(2420Kb)  |  收藏  |  浏览/下载：401/56  |  提交时间：2013/10/16
Autoreactive T-cells  Multiple-sclerosis  Rheumatoid-arthritis  Glatiramer Acetate  Activation  Inflammation  System  Roles  Mice  Differentiation