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Artematrovirenolides A-D and Artematrolides S-Z, Sesquiterpenoid Dimers with Cytotoxicity against Three Hepatoma Cell Lines from Artemisia atrovirens 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 1, 页码: 104-114
作者:  Su,Li-Hua;  Li,Tian-Ze;  Ma,Yun-Bao;  Geng,Chang-An;  Huang,Xiao-Yan;  Zhang,Xin;  Gao,Zhen;  Chen,Ji-Jun
浏览  |  Adobe PDF(2103Kb)  |  收藏  |  浏览/下载：139/50  |  提交时间：2022/04/02
Artemisia atrovirens  Sesquiterpenoid dimers  Structure elucidation  X-ray diffraction  Antihepatoma activity  GUAIANOLIDE  ARGYI  
Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 11, 页码: 2045-2057
作者:  Li, Tian-Ze;  Huang, Xiao-Yan;  Sun, Jin-Jin;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1234Kb)  |  收藏  |  浏览/下载：17/6  |  提交时间：2024/04/30
(+)-Paeoveitol derivatives  Antidepressant  Forced swimming test  Monoamine neurotransmitter  
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：13/4  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
Synthesis and biological evaluation of paeoveitol D derivatives as new melatonin receptor agonists with antidepressant activities 期刊论文
RSC MEDICINAL CHEMISTRY, 2022, 卷号: 13, 期号: 10, 页码: 1212-1224
作者:  Li, Tian-Ze;  Hu, Jing;  Sun, Jin-Jin;  Huang, Xiao-Yan;  Geng, Chang-An;  Liu, Shu-Bai;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(932Kb)  |  收藏  |  浏览/下载：17/6  |  提交时间：2024/04/30
BENZOFURAN  
Triterpenoids from Uncaria rhynchophylla and Their PTP1B Inhibitory Activity 期刊论文
PHYTON-INTERNATIONAL JOURNAL OF EXPERIMENTAL BOTANY, 2022, 卷号: 91, 期号: 8, 页码: 1809-1816
作者:  Luo, Shuaibin;  Zhang, Xuemei;  He, Kang;  Zou, Juan;  Geng, Chang-An
浏览  |  Adobe PDF(486Kb)  |  收藏  |  浏览/下载：52/3  |  提交时间：2024/04/30
Uncaria rhynchophylla  triterpenoids  antidiabetic effects  PTP1B inhibitors  ALKALOIDS  
Lipid Disorders in NAFLD and Chronic Kidney Disease 期刊论文
BIOMEDICINES, 2021, 卷号: 9, 期号: 10, 页码: 1405
作者:  Yang,Meng;  Geng,Chang-An;  Liu,Xinguang;  Guan,Min
收藏  |  浏览/下载：55/0  |  提交时间：2022/04/02
lipid  NAFLD  chronic kidney disease  NONALCOHOLIC FATTY LIVER  ENDOPLASMIC-RETICULUM STRESS  MESENCHYMAL STEM-CELLS  INSULIN-RESISTANCE  LIPOPROTEIN METABOLISM  OBETICHOLIC ACID  RENAL-FIBROSIS  RECEPTOR-ALPHA  MOUSE MODEL  ER STRESS  
Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
作者:  Su,Li-Hua;  Ma,Yun-Bao;  Geng,Chang-An;  Li,Tian-Ze;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xin;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(2611Kb)  |  收藏  |  浏览/下载：138/72  |  提交时间：2022/04/02
Artemisia atrovirens  guaiane-type sesquiterpenoids  artematrovirenins A-P  HepG2 and Huh7 cell lines  antihepatic cytotoxicity  LACTONES  CONSTITUENTS  GUAIANOLIDES  
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
作者:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
浏览  |  Adobe PDF(6313Kb)  |  收藏  |  浏览/下载：92/29  |  提交时间：2022/04/02
Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS  
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：109/31  |  提交时间：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Trimeric and dimeric sesquiterpenoids from Artemisia atrovirens and their cytotoxicities 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2021, 卷号: 8, 期号: 6, 页码: 1249-1256
作者:  Su,Li-Hua;  Li,Tian-Ze;  Geng,Chang-An;  Ma,Yun-Bao;  Huang,Xiao-Yan;  Wang,Jin-Ping;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(1235Kb)  |  收藏  |  浏览/下载：80/38  |  提交时间：2022/04/02