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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：72/11  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Inverse Electron-Demanding Diels-Alder Reactions in the Chemical Synthesis of Prenylated Indole Alkaloids Containing a Bicycle[2.2.2]diazaoctane Moiety: A Theoretical Study 期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2023, 卷号: 18, 期号: 7
作者:  Xu,Wenqiang;  Sun,Tian-Yu;  Di,Yingtong;  Hao,Xiaojiang;  Wu,Yun-Dong
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alkaloids  chemical synthesis  inverse-electron demanding Diels-Alder reaction  reaction mechanisms  theoretical study  BIOMIMETIC TOTAL-SYNTHESIS  CORRELATED MOLECULAR CALCULATIONS  MARINE-DERIVED FUNGUS  GAUSSIAN-BASIS SETS  (-)-VERSICOLAMIDE B  ORBITAL METHODS  BREVIANAMIDE-A  STEPHACIDIN-A  MODEL  CONCISE  
Three New Constituents with Anti-Inflammatory and Antimicrobial Activities in Vitro from the Roots of Capsicum annuum L. 期刊论文
CHEMISTRY & BIODIVERSITY, 2023, 卷号: 20, 期号: 8
作者:  Shi,Jiang;  Deng,Lu-Lu;  Li,Jiang;  Wang,Min;  Fan,Yan-Hua;  Pan,Wei-Dong;  Hao,Xiao-Jiang;  Mu,Shu-Zhen
浏览  |  Adobe PDF(2077Kb)  |  收藏  |  浏览/下载：49/11  |  提交时间：2024/07/10
anti-inflammatory  active constituent  roots of Capsicum annuum L  sesquiterpenes  structural identification  AGRICULTURAL WASTE  SESQUITERPENOIDS  
Artemeriopolides A-D, two types of sesquiterpenoid dimers with rare carbon skeletons from Artemisia eriopoda and their antihepatoma cytotoxicity 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 11, 页码: 2635-2641
作者:  He,Xiao-Feng;  Li,Qi-Hao;  Li,Tian-Ze;  Ma,Yun-Bao;  Dong,Wei;  Yang,Ke-Xin;  Geng,Chang-An;  Zhang,Hao-Wei;  Wang,Yuan;  Chen,Ji-Jun
浏览  |  Adobe PDF(1676Kb)  |  收藏  |  浏览/下载：66/17  |  提交时间：2024/07/22
A clue to the evolutionary history of modern East Asian flora: Insights from phylogeography and diterpenoid alkaloid distribution pattern of the Spiraea japonica complex 期刊论文
MOLECULAR PHYLOGENETICS AND EVOLUTION, 2023, 卷号: 184, 页码: 107772
作者:  Luo,Dong;  Song,Min-shu;  Xu,Bo;  Zhang,Yu;  Zhang,Jian-wen;  Ma,Xiang-guang;  Hao,Xiao jiang;  Sun,Hang
浏览  |  Adobe PDF(12334Kb)  |  收藏  |  浏览/下载：93/17  |  提交时间：2024/07/25
ampliative Spiraea japonica complex  East Asian flora  Transition belt  Phylogeography  Diterpenoid alkaloids  MOLECULAR PHYLOGEOGRAPHY  SECONDARY METABOLITES  HENGDUAN MOUNTAINS  QUATERNARY CLIMATE  PLANT DIVERSITY  ROSACEAE  DNA  CHLOROPLAST  COALESCENT  CHINA  
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 306, 页码: 116158
作者:  Guo,Hui-Hui;  Shen,Hao-Ran;  Tang,Ming-Ze;  Sheng,Ning;  Ding,Xiao;  Lin,Yuan;  Zhang,Jin-Lan;  Jiang,Jian-Dong;  Gao,Tian-Le;  Wang,Lu-Lu;  Han,Yan-Xing
浏览  |  Adobe PDF(14966Kb)  |  收藏  |  浏览/下载：63/14  |  提交时间：2024/07/25
Dengzhan shengmai  Microbiota-gut-brain axis  Short-chain fatty acids  Cerebral ischemia  Gut barrier  Fecal microbiota transplantation  STROKE  SCUTELLARIN  
The Aqueous Extract of Brassica oleracea L. Exerts Phytotoxicity by Modulating H2O2 and O2Levels, Antioxidant Enzyme Activity and Phytohormone Levels 期刊论文
PLANTS-BASEL, 2023, 卷号: 12, 期号: 17, 页码: 3086
作者:  Wang,Yu;  Zhao,Yuanzheng;  Dong,Baozhu;  Wang,Dong;  Hao,Jianxiu;  Jia,Xinyu;  Zhao,Yuxi;  Nian,Yin;  Zhou,Hongyou
浏览  |  Adobe PDF(6434Kb)  |  收藏  |  浏览/下载：92/18  |  提交时间：2024/05/09
allelopathy  reactive oxygen species  antioxidant enzymes  phytohormones  LC-MS  AUXIN  ESTER  
Effects of Climate Change on the Spatial Distribution of the Threatened Species Rhododendron purdomii in Qinling-Daba Mountains of Central China: Implications for Conservation 期刊论文
SUSTAINABILITY, 2023, 卷号: 15, 期号: 4, 页码: 3181
作者:  Dong,Hao;  Zhang,Ningning;  Shen,Simin;  Zhu,Shixin;  Fan,Saibin;  Lu,Yang
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Rhododendron  climate change  MaxEnt  species distribution  conservation  Qinling-Daba Mountains  DIVERSITY  PATTERNS  POPULATIONS  MODELS  MAXENT  IMPACT  TIME  
Prebiotic-Based Nanoamorphous Atorvastatin Attenuates Nonalcoholic Fatty Liver Disease by Retrieving Gut and Liver Health 期刊论文
SMALL STRUCTURES, 2023, 页码: 2200312
作者:  Cui,Jin-Jin;  Li,Rui;  Ma,Xiao-Lei;  Yu,Hao-Yang;  Luo,Zhi-Gang;  Du,Peng;  Ren,Ling;  Ding,Xiao;  Guo,Xiu-Ping;  Zheng,Wen-Sheng;  Jiang,Jian-Dong;  Che,Yongsheng;  Wang,Lu-Lu
浏览  |  Adobe PDF(26415Kb)  |  收藏  |  浏览/下载：82/19  |  提交时间：2024/07/30
atorvastatin  gut flora  nanoamorphous  nonalcoholic fatty liver disease  prebiotics  SOLID DISPERSIONS  STATIN USE  EFFICACY  STEATOHEPATITIS  FORMULATION  SAFETY  ABSORPTION  ACTIVATION  MICROBIOTA  CIRRHOSIS  
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023
作者:  Wang,Yin-Yuan;  Ni,Jian-Cheng;  Zhao,Yue-Qin;  Yang,Xu;  Niu,Zhen-Peng;  Yang,Xing-Zhi;  Dong,Xian-Xiang;  Zhao,Yu-Han;  Hao,Xiao-Jiang;  Ding,Xiao
浏览  |  Adobe PDF(1997Kb)  |  收藏  |  浏览/下载：35/8  |  提交时间：2024/07/31
Iridoid glycosides  Morinda officinalis  lysosomal biogenesis  TFEB/TFE3  antioxidant activity  TRANSCRIPTIONAL CONTROL  TFEB  PHOSPHORYLATION  REVEALS  PATHWAY