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| 瘤果黑种草子和两种紫珠属药用植物化学成分及生物活性研究 学位论文 博士, 2018 作者: 高俊博 Adobe PDF(10360Kb)  |  收藏  |  浏览/下载:50/4  |  提交时间:2021/01/05 |
| 绛县产冬凌草药材的评价 学位论文 : 中国科学院大学, 2017 作者: 张源渊 Adobe PDF(8170Kb)  |  收藏  |  浏览/下载:83/2  |  提交时间:2019/06/14 |
| Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者: Zeng, Guang-Zhi; Fan, Jun-Ting; Xu, Jun-Ju; Li, Yan; Tan, Ning-Hua 浏览  |  Adobe PDF(6299Kb)  |  收藏  |  浏览/下载:255/43  |  提交时间:2015/05/14 One Of The Major compOnents Isolated From The Traditional 2-methyl-1 Chinese Medicine Rubia Yunnanensis 3 Exhibited Inhibitory Activity On The proliferatiOn Of Several 6-trihydroxy-9 HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay 10-anthraquinone (Mta) And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle Arrest In Human Cervical carcInoma Hela Cells. Further Mta Was Found To Induce apopTosis Of Hela Cells Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And Release Of Cytochrome c Into The Cytosol Which Caused The Cleavage Of Caspase And Poly(Adp-ribose) Polymerase And Finally Triggered The Apoptosis. furThermore The P53/p21/cdc2-cyclin B1 Signaling Was Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of R. Yunnanensis a Folk Anti-cancer Herb Used In Yunnan China. |
| Draft Genome of the Filarial Nematode Parasite Brugia malayi 期刊论文 Science, 2007, 卷号: 317, 页码: 1756-1760 作者: Elodie Ghedin; Shiliang Wang; David Spiro; Elisabet Caler; Qi Zhao; Jonathan Crabtree; Jonathan E. Allen; Arthur L. Delcher; David B. Guiliano; Diego Miranda-Saavedra; Samuel V. Angiuoli; Todd Creasy; Paolo Amedeo; Brian Haas; Najib M. El-Sayed; Jennifer R. Wortman; Tamara Feldblyum; Luke Tallon; Michael Schatz; Martin Shumway; Hean Koo; Steven L. Salzberg; Seth Schobel; Mihaela Pertea; Mihai Pop; Owen White; Geoffrey J. Barton; Clotilde K. S. Carlow; Michael J. Crawford; Jennifer Daub; Matthew W. Dimmic; Chris F. Estes; Jeremy M. Foster; Mehul Ganatra; William F. Gregory; Nicholas M. Johnson; Jinming Jin; Richard Komuniecki; Ian Korf; Sanjay Kumar; Sandra Laney; Ben-Wen Li; Wen Li; Tim H. Lindblom; Sara Lustigman; Dong Ma; Claude Maina; David Martin; James P. McCarter; Larry McReynolds; Makedonka Mitreva; Thomas B. Nutman; John Parkinson; José M. Peregrín-Alvarez; Catherine Poole; Qinghu Ren; Lori Saunders; Ann E. Sluder; Katherine Smith; Mario Stanke; Thomas R. Unnasch; Jenna Ware; Aguan D. Wei; Gary Weil; Deryck J. Williams; Yinhua Zhang; Steven A. Williams; Claire Fraser-Liggett; Barton Slatko; Mark L. Blaxter; Alan L. Scott Adobe PDF(4058Kb)  |  收藏  |  浏览/下载:89/1  |  提交时间:2015/09/09 |
| Biochemistry of Signal Transduction and Regulation 3rd ed 专著 WILEY-VCH Verlag:WILEY-VCH Verlag, 2003 Gerhard Krauss Adobe PDF(7790Kb)  |  收藏  |  浏览/下载:96/5  |  提交时间:2013/10/30 |
| MOLECULAR.CELL.BIOLOGY 5TH.ED 专著 , 2003 H. Lodish Adobe PDF(62274Kb)  |  收藏  |  浏览/下载:89/8  |  提交时间:2014/05/27 |
| Gene Regulation and Metabolism Postgenomic Computational Approaches 专著 London:MIT Press, 2002 Julio Collado-Vides; Ralf Hofestadt Adobe PDF(5104Kb)  |  收藏  |  浏览/下载:61/5  |  提交时间:2013/10/30 |
| Principles of Genetics 7th Ed. 专著 , 2001 John.Belote Adobe PDF(67813Kb)  |  收藏  |  浏览/下载:101/6  |  提交时间:2014/05/27 |