中文版 | English

在结果中检索

KIB OpenIR

浏览/检索结果: 共27条，第1-10条 帮助

限定条件    
已选(0)清除 条数/页：   排序方式：
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：231/36  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 10
作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li;  Liu, Xingyong;  Yuan, Feng;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：151/0  |  提交时间：2020/03/02
Artemisinin  Quinazoline  Hybridization  Colorectal cancer  Chemotherapy  
Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1889-1906
作者:  Li, Yaping;  Wu, Dong-mei;  Kong, Ling-mei;  Zhang, Shuqun;  Du, Haibo;  Sun, Wei;  Zhang, Li;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：184/0  |  提交时间：2020/03/26
bioassay  ensemble docking  scoring function  virtual screening  Wee1 inhibitors  
The complete chloroplast genome of Primula bulleyana, a popular ornamental species 期刊论文
MITOCHONDRIAL DNA PART B-RESOURCES, 2019, 卷号: 4, 期号: 2, 页码: 3673-3674
作者:  Chen, Xiong;  Zhang, Li;  Li, Wenqing;  Huang, Yuan;  Wu, Zhikun
浏览  |  Adobe PDF(741Kb)  |  收藏  |  浏览/下载：192/40  |  提交时间：2019/12/20
Complete chloroplast genome  Primula bulleyana  ornamental species  
Rapid evolution of protein diversity by de novo origination in Oryza 期刊论文
NATURE ECOLOGY & EVOLUTION, 2019, 卷号: 3, 期号: 4, 页码: 679-690
作者:  Zhang, Li;  Ren, Yan;  Yang, Tao;  Li, Guangwei;  Chen, Jianhai;  Gschwend, Andrea R.;  Yu, Yeisoo;  Hou, Guixue;  Zi, Jin;  Zhou, Ruo;  Wen, Bo;  Zhang, Jianwei;  Chougule, Kapeel;  Wang, Muhua;  Copetti, Dario;  Peng, Zhiyu;  Zhang, Chengjun;  Zhang, Yong;  Ouyang, Yidan;  Wing, Rod A.;  Liu, Siqi;  Long, Manyuan
浏览  |  Adobe PDF(1636Kb)  |  收藏  |  浏览/下载：274/60  |  提交时间：2019/07/29
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Liu, Xingyong;  Zhang, Li;  Wang, Liang-Liang;  Zuo, Zhili
浏览  |  Adobe PDF(7335Kb)  |  收藏  |  浏览/下载：271/31  |  提交时间：2019/07/29
Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator  
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(2732Kb)  |  收藏  |  浏览/下载：287/47  |  提交时间：2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS  
Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying;  Liu, Xingyong;  Siddique, Abu Nasar;  Zhang, Li;  Zuo, Zhili
收藏  |  浏览/下载：162/0  |  提交时间：2018/11/12
Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations  
Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915
作者:  Li, Yaping;  Pu, Yinglan;  Liu, Hui;  Zhang, Li;  Liu, Xingyong;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：434/0  |  提交时间：2018/11/06
Wee1 inhibitors  Pharmacophore model  Molecular docking  Virtual screening  Molecular dynamics simulation  
Pharmacophore modeling, molecular docking and molecular dynamics studies on natural products database to discover novel skeleton as non-puricie xanthine oxidase inhibitors 期刊论文
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2018, 卷号: 38, 期号: 3, 页码: 246-255
作者:  Peng, Jiale;  Li, Yaping;  Zhou, Yeheng;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
收藏  |  浏览/下载：169/0  |  提交时间：2019/03/29