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Selected Mutations Revealed Intermediates and Key Precursors in the Biosynthesis of Polyketide-Terpenoid Hybrid Sesquiterpenyl Epoxy-cyclohexenoids 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 14, 页码: 3923-3926
作者:  Teng, Lin-Lin;  Song, Tian-Yang;  Xu, Zi-Fei;  Liu, Xiao;  Dai, Rong;  Chen, Yong-Hong;  Li, Sheng-Hong;  Zhang, Ke-Qin;  Niu, Xue-Mei
浏览  |  Adobe PDF(1132Kb)  |  收藏  |  浏览/下载:285/103  |  提交时间:2017/10/23
Fungus Arthrobotrys-oligospora  Morphological Regulatory Arthrosporols  Metabolite Production  Antibiotics  Disruption  Mechanisms  Patulin  
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载:344/67  |  提交时间:2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载:257/86  |  提交时间:2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
Four new steroids from the endophytic fungus Chaetomium sp M453 derived of Chinese herbal medicine Huperzia serrata 期刊论文
FITOTERAPIA, 2017, 卷号: 117, 页码: 41-46
作者:  Yu, Fei-Xue;  Li, Zhe;  Chen, Yao;  Yang, Yin-He;  Li, Guo-Hong;  Zhao, Pei-Ji
浏览  |  Adobe PDF(450Kb)  |  收藏  |  浏览/下载:262/93  |  提交时间:2017/05/19
Huperzia Serrata  Endophytic Fungus  Chaetomium Sp M453  C25 Steroids  X-ray  Structure Identification