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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载:289/1  |  提交时间:2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
作者:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
Adobe PDF(425Kb)  |  收藏  |  浏览/下载:103/1  |  提交时间:2017/07/21
Site-Divergent Delivery of Terminal Propargyls to Carbohydrates by Synergistic Catalysis 期刊论文
Chem, 2017, 页码: 834-845
作者:  Ren-Zhe Li;  Hua Tang;  Liqiang Wan;  Xia Zhang;  hengyanFu1JieLiu;  Shengyong Yang;  Da Jia;  Dawen Niu
Adobe PDF(2237Kb)  |  收藏  |  浏览/下载:102/0  |  提交时间:2017/11/17
Synthesis and antitumor activity of novel N-substituted tetrahydro-β-carboline–imidazolium salt derivatives 期刊论文
Org. Biomol. Chem., 2016, 卷号: 14, 页码: 9423
作者:  Bei Zhou
Adobe PDF(1764Kb)  |  收藏  |  浏览/下载:56/0  |  提交时间:2017/08/23
Design, Synthesis, and Biological Evaluation of Novel Benzofuran Derivatives Bearing N-Aryl Piperazine Moiety 期刊论文
Molecules, 2016, 卷号: 21, 页码: 1684
作者:  Yulu Ma
Adobe PDF(907Kb)  |  收藏  |  浏览/下载:56/0  |  提交时间:2017/08/21
Insights into the unexpected chemoselectivity in Brønsted acid catalyzed cyclization of isatins with enaminones: convenient synthesis of pyrrolo[3,4- c]quinolin-1-ones and spirooxindoles 期刊论文
chem comm, 2016, 卷号: 52, 页码: 8002
作者:  Hui Xu
Adobe PDF(2347Kb)  |  收藏  |  浏览/下载:37/0  |  提交时间:2017/08/18
The re‑emergence of natural products for drug discovery in the genomics era 期刊论文
Nature Reviews Drug Discovery, 2015, 页码: nrd4510
作者:  Alan L. Harvey
Adobe PDF(540Kb)  |  收藏  |  浏览/下载:88/0  |  提交时间:2017/08/22
Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark 期刊论文
nature CHEMICAL BIOLOGY, 2014, 卷号: 10, 期号: 0, 页码: 365-373
作者:  Lunzhi Dai;  Chao Peng;  Emilie Montellier;  Zhike Lu;  Yue Chen;  Haruhiko Ishii;  Alexandra Debernardi;  Thierry Buchou;  Sophie Rousseaux;  Fulai Jin;  Benjamin R Sabari;  Zhiyou Deng;  C David Allis;  Bing Ren;  Saadi Khochbin;  Yingming Zhao
Adobe PDF(1595Kb)  |  收藏  |  浏览/下载:61/1  |  提交时间:2017/07/24
Molecular mechanism of strigolactone perceptionby DWARF14 期刊论文
NATURE COMMUNICATIONS, 2013, 期号: 0, 页码: 1—10
作者:  Hidemitsu Nakamura;  You-Lin Xue;  Takuya Miyakawa;  Feng Hou;  Hui-Min Qin;  Kosuke Fukui;  Xuan Shi;  Emi Ito;  Shinsaku Ito;  Seung-Hyun Park;  Yumiko Miyauchi;  Atsuko Asano;  Naoya Totsuka;  akashi Ueda;  Masaru Tanokura;  Tadao Asami
Adobe PDF(1044Kb)  |  收藏  |  浏览/下载:38/1  |  提交时间:2017/07/21
A high-throughput screen for quorum-sensinginhibitors that target acyl-homoserinelactone synthases 期刊论文
PNAS, 2013, 卷号: 110, 期号: 34, 页码: 13815–13820
作者:  Quin H. Christensen;  Tyler L. Grove;  Squire J. Booker;  E. Peter Greenberg
Adobe PDF(529Kb)  |  收藏  |  浏览/下载:59/1  |  提交时间:2017/07/21