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Iridium-Catalyzed Enantioselective Indole Cyclization: Application to the Total Synthesis and Absolute Stereochemical Assignment of (-)-AspidophyllineA 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 12, 页码: 4044-4048
作者:  Jiang, Shi-Zhi;  Zeng, Xue-Yi;  Liang, Xiao;  Lei, Ting;  Wei, Kun;  Yang, Yu-Rong
浏览  |  Adobe PDF(1053Kb)  |  收藏  |  浏览/下载：351/61  |  提交时间：2016/08/22
Cyclizations  Enantioselectivity  Indoles  Iridium  Total Synthesis  
Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：336/76  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Copper-Mediated Dimerization to Access 3a,3a '-'Bispyrrolidinoindoline: Diastereoselective Synthesis of (+)-WIN 64821 and (-)-Ditryptophenaline 期刊论文
ORGANIC LETTERS, 2015, 卷号: 17, 期号: 2, 页码: 206-209
作者:  Liang, Kangjiang;  Deng, Xu;  Tong, Xiaogang;  Li, Dashan;  Ding, Ming;  Zhou, Ankun;  Xia, Chengfeng;  Xia,CF (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  xiachengfeng@mail.kib.ac.cn
浏览  |  Adobe PDF(629Kb)  |  收藏  |  浏览/下载：396/46  |  提交时间：2015/06/29
Synthesis and conformation studies of rubiyunnanin B analogs 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 37, 页码: 6630-6640
作者:  Liu, Na-Na;  Zhao, Si-Meng;  Zhao, Jing-Feng;  Zeng, Guang-Zhi;  Tan, Ning-Hua;  Liu, Jian-Ping;  Tan, NH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China.;  nhtan@mail.kib.ac.cn;  jpliu@ynu.edu.cn
Adobe PDF(619Kb)  |  收藏  |  浏览/下载：216/50  |  提交时间：2014/10/11
Rubiyunnanin b Analogs  Synthesis  Conformation Studies  Bioactivities  
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载：309/74  |  提交时间：2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Griseusins F and G, Spiro-Naphthoquinones from a Tin Mine Tailings-Derived Alkalophilic Nocardiopsis Species 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2012, 卷号: 75, 期号: 11, 页码: 1994-1998
作者:  Ding, Zhang-Gui;  Zhao, Jiang-Yuan;  Li, Ming-Gang;  Huang, Rong;  Li, Qing-Ming;  Cui, Xiao-Long;  Zhu, Hua-Jie;  Wen, Meng-Liang
Adobe PDF(290Kb)  |  收藏  |  浏览/下载：577/112  |  提交时间：2013/01/22
Streptomyces-griseus  Biological-activity  Antibiotics  Pyranonaphthoquinones  Dihydrofusarubin  Configuration  
Development of novel conformation-constrained cytotoxic derivatives of cheliensisin A by embedment of small heterocycles 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 9, 页码: 4238-4244
作者:  Deng, Xu;  Su, Jia;  Zhao, Yu;  Peng, Li-Yan;  Li, Yan;  Yao, Zhu-Jun;  Zhao, Qin-Shi
Adobe PDF(450Kb)  |  收藏  |  浏览/下载：392/98  |  提交时间：2012/03/16
Cheliensisin a  Derivative  Structure-activity Relationship  Cytotoxicity  Anticancer  
Design, synthesis and cytotoxic activities of novel hybrid compounds between dihydrobenzofuran and imidazole 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2011, 卷号: 9, 期号: 11, 页码: 4250-4255
作者:  Chen, Wen;  Yang, Xiao-Dong;  Li, Yan;  Yang, Li-Juan;  Wang, Xue-Quan;  Zhang, Gao-Lan;  Zhang, Hong-Bin
Adobe PDF(511Kb)  |  收藏  |  浏览/下载：279/103  |  提交时间：2012/07/25
Biological Evaluation  Antitumor-activity  Derivatives  Iodides  Analogs  Lignans  Trans  Dna  
Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 1, 页码: 307-319
作者:  Guo, Rui-Hua;  Zhang, Quan;  Ma, Yun-Bao;  Luo, Jie;  Geng, Chang-An;  Wang, Li-Jun;  Zhang, Xue-Mei;  Zhou, Jun;  Jiang, Zhi-Yong;  Chen, Ji-Jun
Adobe PDF(866Kb)  |  收藏  |  浏览/下载：359/91  |  提交时间：2012/04/10
Anti-hepatitis b Virus Activity  Quinolin-2(1h)-one  Structure-activity Relationships  
Total synthesis of pulverolide: revision of its structure 期刊论文
TETRAHEDRON LETTERS, 2010, 卷号: 51, 期号: 37, 页码: 4874-4876
作者:  Yang, Wanqiu;  Liu, Jikai;  Zhang, Hongbin
Adobe PDF(449Kb)  |  收藏  |  浏览/下载：276/111  |  提交时间：2012/03/21
Pulverolide  Butenolide  Total Synthesis  Revision Of Structure