The Chemistry and Biology of Lycopodium Alkaloids

doi:10.1002/cbdv.202400954

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	The Chemistry and Biology of Lycopodium Alkaloids
	Zhang, Zhi-Jun; Jiang, Shuai; Zhao, Qin-Shi
	2024
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
卷号	21 期号:8 页码:-
摘要	Lycopodiales, an order comprising 388 distinct species, is the source of Lycopodium alkaloids (LAs), a group of naturally occurring alkaloids that share a common biosynthesis and structural attributes. These remarkable organisms are considered vestiges of ancient ferns, with fossil evidence dating their existence back to an impressive 300 million years. LAs usually are tricyclic or tetracyclic compounds with C16N or C16N2 skeleton. But then there are also have a few C11N, C15N, C15N2, C22N2, and C27N3 skeleton. LAs have attracted much scientific attention because of their important biological activities related to acetylcholinesterase and unique structural characteristics. From 1881 to December 2023, there are 593 LAs from 49 species of Lycopodiales have been reported. Because the total amount of LAs is nearly five times that of 1994, the classification and group allocation of some newly isolated LAs is often challenging and not unambiguous by Ayer's simple classification. This review makes a more systematic and detailed classification for it and provides extensive coverage of naturally occurring LAs discovered from 1881 to December 2023. Until now, there is no comprehensively summary of biological activity of the LAs. This review is the first time covered the biological activity of the all LAs.
DOI	10.1002/cbdv.202400954
WOS记录号	WOS:001281634400001
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/76289
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhang, Zhi-Jun,Jiang, Shuai,Zhao, Qin-Shi. The Chemistry and Biology of Lycopodium Alkaloids[J]. CHEMISTRY & BIODIVERSITY,2024,21(8):-.
APA	Zhang, Zhi-Jun,Jiang, Shuai,&Zhao, Qin-Shi.(2024).The Chemistry and Biology of Lycopodium Alkaloids.CHEMISTRY & BIODIVERSITY,21(8),-.
MLA	Zhang, Zhi-Jun,et al."The Chemistry and Biology of Lycopodium Alkaloids".CHEMISTRY & BIODIVERSITY 21.8(2024):-.

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