Four unreported aporphine alkaloids with antifungal activities from Artabotrys hexapetalus

doi:10.1016/j.fitote.2024.105868

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	Four unreported aporphine alkaloids with antifungal activities from Artabotrys hexapetalus
	Zhao, Pei; Yu, Zhiyin; Huang, Jian-Ping; Wang, Li; Huang, Sheng-Xiong; Yang, Jing
	2024
发表期刊	FITOTERAPIA
ISSN	0367-326X
卷号	174 页码:105868
摘要	In this study, the extract from Artabotrys hexapetalus showed strong antifungal activity against phytopathogenic fungi in vitro. Four unreported aporphine alkaloids, hexapetalusine A -D (1-4), were isolated from stems and roots of Artabotrys hexapetalus (L.f.) Bhandari, along with six known aporphine alkaloids (5-10). Their chemical structures were elucidated by extensive spectroscopic analysis. The absolute configurations of 1-3 were determined using single -crystal X-ray diffractions and ECD calculations. Hexapetalusine A -C (1-3) were special amidic isomers. Additionally, all isolated compounds were evaluated for their antifungal activity against four phytopathogenic fungi in vitro. Hexapetalusine D (4) exhibited weak antifungal activity against Curvularia lunata. Liriodenine (5) displayed significant antifungal activity against Fusarium proliferatum and Fusarium oxysporum f. sp. vasinfectum, which is obviously better than positive control nystatin, suggesting that it had great potential to be developed into an effective and eco-friendly fungicide.
DOI	10.1016/j.fitote.2024.105868
WOS记录号	WOS:001188932700001
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/76274
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhao, Pei,Yu, Zhiyin,Huang, Jian-Ping,et al. Four unreported aporphine alkaloids with antifungal activities from Artabotrys hexapetalus[J]. FITOTERAPIA,2024,174:105868.
APA	Zhao, Pei,Yu, Zhiyin,Huang, Jian-Ping,Wang, Li,Huang, Sheng-Xiong,&Yang, Jing.(2024).Four unreported aporphine alkaloids with antifungal activities from Artabotrys hexapetalus.FITOTERAPIA,174,105868.
MLA	Zhao, Pei,et al."Four unreported aporphine alkaloids with antifungal activities from Artabotrys hexapetalus".FITOTERAPIA 174(2024):105868.

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