A Modified 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples

doi:10.3390/ijms241411272

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	A Modified 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples
	Li,Yue-Chiun; Wu,Chia-Hung; Le,Thi Ha; Yuan,Qingjun; Huang,Luqi; Chen,Guo-Fen; Yang,Mei-Lin; Lam,Sio-Hong; Hung,Hsin-Yi; Sun,Handong; Wu,Yi-Hung; Kuo,Ping-Chung; Wu,Tian-Shung
	2023
发表期刊	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN	1422-0067
卷号	24 期号:14 页码:11272
摘要	A previous H-1-NMR method allowed the quantification of ephedrine alkaloids; however, there were some disadvantages. The cyclized derivatives resulted from the impurities of diethyl ether were identified and benzene was selected as the better extraction solvent. The locations of ephedrine alkaloids were confirmed with 2D NMR. Therefore, a specific H-1-NMR method has been modified for the quantification of ephedrine alkaloids. Accordingly, twenty Ephedrae Herba samples could be classified into three classes: (I) E. sinica-like species; (II) E. intermedia-like species; (III) others (lower alkaloid contents). The results indicated that ephedrine and pseudoephedrine are the major alkaloids in Ephedra plants, but the concentrations vary greatly determined by the plant species and the collection locations.
关键词	ephedrine alkaloid Ephedrae Herba cyclized derivative quantitative nuclear magnetic resonance spectroscopy (qNMR) two-dimensional NMR (2D NMR) QUANTITATIVE-ANALYSIS PSEUDOEPHEDRINE CHROMATOGRAPHY URINE SINICA (-)-EPHEDRINE SUPPLEMENTS EXTRACTION DRUGS
DOI	10.3390/ijms241411272
WOS记录号	WOS:001035857200001
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75016
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Li,Yue-Chiun,Wu,Chia-Hung,Le,Thi Ha,et al. A Modified 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2023,24(14):11272.
APA	Li,Yue-Chiun.,Wu,Chia-Hung.,Le,Thi Ha.,Yuan,Qingjun.,Huang,Luqi.,...&Wu,Tian-Shung.(2023).A Modified 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,24(14),11272.
MLA	Li,Yue-Chiun,et al."A Modified 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24.14(2023):11272.

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