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Meroterpenoids and alkaloids from Ganoderma australe
Zhang,Jiao-Jiao; Dong,Yun; Qin,Fu-Ying; Yan,Yong-Ming; Cheng,Yong-Xian
2021
发表期刊NATURAL PRODUCT RESEARCH
ISSN1478-6419
卷号35期号:19页码:3226-3232
摘要Two new mertoterpenoids, australins A (1) and B (2), and a new alkaloid, australine (4), together with five known compounds (3, 5-8) were isolated from the fruiting bodies of Ganoderma australe. Their structures including absolute configurations were assigned by using spectroscopic methods and electronic circular dichroism (ECD) calculations. Racemic australin A was further purified by chiral HPLC. Biological assessments reveal that compounds (+)-1 and 7 could significantly protect SH-SY5Y cells from glutamate-induced neural excitotoxicity.
关键词Ganoderma australe meroterpenoids alkaloids neuroprotection LUCIDUM INHIBITORS EXTRACT POTENT
DOI10.1080/14786419.2019.1693565
WOS记录号WOS:000497137300001
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/73742
专题中国科学院昆明植物研究所
作者单位1.Shenzhen Univ, Sch Pharmaceut Sci, Hlth Sci Ctr, Shenzhen, Guangdong, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China
3.Chinese Acad Sci, Brain Cognit & Brain Dis Inst, Shenzhen Inst Adv Technol, Shenzhen, Guangdong, Peoples R China
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Zhang,Jiao-Jiao,Dong,Yun,Qin,Fu-Ying,et al. Meroterpenoids and alkaloids from Ganoderma australe[J]. NATURAL PRODUCT RESEARCH,2021,35(19):3226-3232.
APA Zhang,Jiao-Jiao,Dong,Yun,Qin,Fu-Ying,Yan,Yong-Ming,&Cheng,Yong-Xian.(2021).Meroterpenoids and alkaloids from Ganoderma australe.NATURAL PRODUCT RESEARCH,35(19),3226-3232.
MLA Zhang,Jiao-Jiao,et al."Meroterpenoids and alkaloids from Ganoderma australe".NATURAL PRODUCT RESEARCH 35.19(2021):3226-3232.
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