Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina

doi:10.1021/acs.orglett.9b01453

	Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina
	Wu, Jing 1,2; Yu, Yang 1,2; Wang, Yi 3; Bao, Mei-Fen 1; Shi, Bao-Bao 1,2; Schinnerl, Johann 4; Cai, Xiang-Hai1
通讯作者	Cai, Xiang-Hai(xhcai@mail.kib.ac.cn)
	2019-06-21
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	21 期号:12 页码:4554-4558
摘要	Four unprecedented yellow alkaloids named as taberbovines A-D (1-4) were isolated from stems of Tabernaemontana bovina Lour. Their structures were elucidated by the comprehensive spectroscopic data, computational chemistry, and X-ray crystal diffraction. Alkaloids 1-4 possessed a unique 6/6/5/6/5 ring system and were assigned to monoterpenoid quinolines. Biosynthetically, the isolated alkaloids may be derived from Aspidosperma-type alkaloid by oxidation and rearrangements. Taberbovines A-D exhibited the good inhibitory activities of formation NO in LPS induced RAW264.7 macrophages.
DOI	10.1021/acs.orglett.9b01453
收录类别	SCI
语种	英语
WOS记录号	WOS:000473116000033
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/67838
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Cai, Xiang-Hai
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Bristol Myers Squibb Co, Lawrenceville, NJ 08648 USA 4.Univ Vienna, Div Systemat & Evolutionary Bot, Chemodivers Res Grp, Rennweg 14, A-1030 Vienna, Austria
推荐引用方式 GB/T 7714	Wu, Jing,Yu, Yang,Wang, Yi,et al. Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina[J]. ORGANIC LETTERS,2019,21(12):4554-4558.
APA	Wu, Jing.,Yu, Yang.,Wang, Yi.,Bao, Mei-Fen.,Shi, Bao-Bao.,...&Cai, Xiang-Hai.(2019).Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina.ORGANIC LETTERS,21(12),4554-4558.
MLA	Wu, Jing,et al."Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina".ORGANIC LETTERS 21.12(2019):4554-4558.

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