| Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina | |
Wu, Jing1,2; Yu, Yang1,2; Wang, Yi3; Bao, Mei-Fen1; Shi, Bao-Bao1,2; Schinnerl, Johann4; Cai, Xiang-Hai1
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| Corresponding Author | Cai, Xiang-Hai(xhcai@mail.kib.ac.cn) |
| 2019-06-21 | |
| Source Publication | ORGANIC LETTERS
 |
| ISSN | 1523-7060 |
| Volume | 21Issue:12Pages:4554-4558 |
| Abstract | Four unprecedented yellow alkaloids named as taberbovines A-D (1-4) were isolated from stems of Tabernaemontana bovina Lour. Their structures were elucidated by the comprehensive spectroscopic data, computational chemistry, and X-ray crystal diffraction. Alkaloids 1-4 possessed a unique 6/6/5/6/5 ring system and were assigned to monoterpenoid quinolines. Biosynthetically, the isolated alkaloids may be derived from Aspidosperma-type alkaloid by oxidation and rearrangements. Taberbovines A-D exhibited the good inhibitory activities of formation NO in LPS induced RAW264.7 macrophages. |
| DOI | 10.1021/acs.orglett.9b01453 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000473116000033 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/67838 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Corresponding Author | Cai, Xiang-Hai |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Bristol Myers Squibb Co, Lawrenceville, NJ 08648 USA 4.Univ Vienna, Div Systemat & Evolutionary Bot, Chemodivers Res Grp, Rennweg 14, A-1030 Vienna, Austria |
| Recommended Citation GB/T 7714 | Wu, Jing,Yu, Yang,Wang, Yi,et al. Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina[J]. ORGANIC LETTERS,2019,21(12):4554-4558. |
| APA | Wu, Jing.,Yu, Yang.,Wang, Yi.,Bao, Mei-Fen.,Shi, Bao-Bao.,...&Cai, Xiang-Hai.(2019).Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina.ORGANIC LETTERS,21(12),4554-4558. |
| MLA | Wu, Jing,et al."Four Yellow Monoterpenoid Quinoline Alkaloids from the Stem of Tabernaemontana bovina".ORGANIC LETTERS 21.12(2019):4554-4558. |
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| Wu-2019-Four Yellow （1030KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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