Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana.

	Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana.
	Yin, Xia; Feng, Tao; Li, Zheng-Hui; Leng, Ying; Liu, Ji-Kai
	2014
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	4 期号:3 页码:149-55
摘要	Five new guanacastane-type diterpenes, named guanacastepenes P-T (1-5), were isolated from cultures of the fungus Psathyrella candolleana. Their structures were elucidated on the basis of extensive spectroscopic methods. All of the compounds were tested for their 11beta-hydroxysteroid dehydrogenase (11beta-HSD1) inhibitory activity. Compound 3 exhibited inhibitory activity against both human and mouse isozymes of 11beta-HSD1 with IC50 values of 6.2 and 13.9muM, respectively.
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64917
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Yin, Xia,Feng, Tao,Li, Zheng-Hui,et al. Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana.[J]. Natural products and bioprospecting,2014,4(3):149-55.
APA	Yin, Xia,Feng, Tao,Li, Zheng-Hui,Leng, Ying,&Liu, Ji-Kai.(2014).Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana..Natural products and bioprospecting,4(3),149-55.
MLA	Yin, Xia,et al."Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana.".Natural products and bioprospecting 4.3(2014):149-55.